RSS

Biology

Tag

So­ciety Is Fixed, Biol­ogy Is Mutable

Scott AlexanderSep 11, 2014, 12:27 AM
49 points
1 comment3 min readLW link

There’s no such thing as a tree (phy­lo­ge­net­i­cally)

eukaryoteMay 3, 2021, 3:47 AM
338 points
59 comments8 min readLW link2 reviews
(eukaryotewritesblog.com)

Naked mole-rats: A case study in biolog­i­cal weirdness

eukaryoteMay 19, 2019, 6:40 PM
95 points
14 comments3 min readLW link
(eukaryotewritesblog.com)

Book Re­view: De­sign Prin­ci­ples of Biolog­i­cal Circuits

johnswentworthNov 5, 2019, 6:49 AM
222 points
24 comments12 min readLW link1 review

Why Yud­kowsky is wrong about “co­va­lently bonded equiv­a­lents of biol­ogy”

titotalDec 6, 2023, 2:09 PM
44 points
41 comments1 min readLW link
(open.substack.com)

Im­mune, In a Nutshell

JsevillamolJan 31, 2022, 11:07 PM
51 points
4 comments17 min readLW link

5. Mo­ral Value for Sen­tient An­i­mals? Alas, Not Yet

RogerDearnaleyDec 27, 2023, 6:42 AM
33 points
41 comments23 min readLW link

The Liv­ing Planet In­dex: A Case Study in Statis­ti­cal Pitfalls

Jan_KulveitJun 24, 2024, 10:05 AM
24 points
0 comments4 min readLW link
(www.nature.com)

Will the grow­ing deer prion epi­demic spread to hu­mans? Why not?

eukaryoteJun 25, 2023, 4:31 AM
170 points
33 comments13 min readLW link
(eukaryotewritesblog.com)

How to Make Superbabies

Feb 19, 2025, 8:39 PM
565 points
327 comments31 min readLW link

LW Biol­ogy 101 In­tro­duc­tion: Con­strain­ing Anticipation

virtualAdeptMay 25, 2011, 12:32 AM
70 points
29 comments6 min readLW link

The 2021 Less Wrong Dar­win Game

lsusrSep 24, 2021, 9:16 PM
162 points
102 comments9 min readLW link

Brain Effi­ciency: Much More than You Wanted to Know

jacob_cannellJan 6, 2022, 3:38 AM
200 points
103 comments29 min readLW link

What is “pro­tein fold­ing”? A brief explanation

jasoncrawfordDec 1, 2020, 2:46 AM
74 points
8 comments4 min readLW link
(rootsofprogress.org)

There is way too much serendipity

MalmesburyJan 19, 2024, 7:37 PM
375 points
56 comments7 min readLW link

Protein Re­in­force­ment and DNA Consequentialism

Eliezer YudkowskyNov 13, 2007, 1:34 AM
62 points
20 comments4 min readLW link

how birds sense mag­netic fields

bhauthJun 27, 2024, 6:59 PM
51 points
4 comments5 min readLW link
(www.bhauth.com)

grey goo is unlikely

bhauthApr 17, 2023, 1:59 AM
158 points
123 comments9 min readLW link2 reviews
(bhauth.com)

The two-headed bacterium

MalmesburyAug 10, 2021, 3:28 PM
73 points
4 comments7 min readLW link

Digi­tal brains beat biolog­i­cal ones be­cause diffu­sion is too slow

GeneSmithAug 26, 2023, 2:22 AM
78 points
21 comments5 min readLW link

As­sor­ta­tive Mat­ing And Autism

Scott AlexanderJan 28, 2020, 6:20 PM
50 points
2 comments4 min readLW link
(slatestarcodex.com)

Play­ing the game vs. find­ing a cheat code

MetacelsusSep 10, 2023, 6:11 PM
32 points
1 comment3 min readLW link
(open.substack.com)

The Talk: a brief ex­pla­na­tion of sex­ual dimorphism

MalmesburySep 18, 2023, 4:23 PM
519 points
75 comments16 min readLW link3 reviews

Biolog­i­cal DOOM: a brief overview of biolog­i­cal computation

MetacelsusApr 29, 2023, 8:02 PM
53 points
2 comments6 min readLW link
(denovo.substack.com)

What it’s like to dis­sect a cadaver

Alok SinghNov 10, 2022, 6:40 AM
208 points
24 comments5 min readLW link
(alok.github.io)

Mini ad­vent cal­en­dar of Xrisks: syn­thetic biology

Stuart_ArmstrongDec 4, 2012, 11:15 AM
8 points
26 comments1 min readLW link

Stomach Ulcers and Den­tal Cavities

MetacelsusAug 5, 2023, 2:08 PM
57 points
7 comments1 min readLW link
(denovo.substack.com)

Fra­ter­nal Birth Order Effect and the Ma­ter­nal Im­mune Hypothesis

BuckyOct 4, 2023, 9:18 PM
20 points
1 comment2 min readLW link

PCR retrospective

bhauthDec 26, 2024, 9:20 PM
24 points
0 comments8 min readLW link
(bhauth.com)

Book re­view: Why we sleep

Richard_NgoSep 19, 2018, 10:36 PM
51 points
18 comments5 min readLW link
(thinkingcomplete.blogspot.com)

[Question] How good are our mouse mod­els (psy­chol­ogy, biol­ogy, medicine, etc.), ig­nor­ing trans­la­tion into hu­mans, just in terms of un­der­stand­ing mice? (Same ques­tion for drosophila.)

RubyJan 22, 2021, 8:45 PM
60 points
10 comments1 min readLW link

Book Re­view—Other Minds: The Oc­to­pus, the Sea, and the Deep Ori­gins of Consciousness

Vaughn PapenhausenDec 3, 2018, 8:00 AM
36 points
18 comments16 min readLW link

The AI Revolu­tion in Biology

Roman LeventovMay 26, 2024, 9:30 AM
13 points
0 comments1 min readLW link
(www.cognitiverevolution.ai)

[Question] Why is cap­nom­e­try biofeed­back not more widely known?

riceissaDec 21, 2023, 2:42 AM
20 points
22 comments4 min readLW link

Dy­ing Outside

HalFinneyOct 5, 2009, 2:45 AM
401 points
91 comments2 min readLW link

Maybe An­tivirals aren’t a Use­ful Pri­or­ity for Pan­demics?

DavidmanheimJun 20, 2021, 10:04 AM
24 points
13 comments4 min readLW link

[Question] What does know­ing the her­i­ta­bil­ity of a trait tell me in prac­tice?

Kaj_SotalaJul 26, 2021, 4:29 PM
58 points
22 comments4 min readLW link

legged robot scal­ing laws

bhauthJan 20, 2024, 5:45 AM
34 points
8 comments7 min readLW link
(www.bhauth.com)

A Con­fused Chemist’s Re­view of AlphaFold 2

J BostockSep 27, 2021, 11:10 AM
24 points
4 comments5 min readLW link

[Book Re­view] “The Vi­tal Ques­tion” by Nick Lane

lsusrSep 27, 2021, 10:50 PM
70 points
28 comments5 min readLW link

[Book re­view] Who we are and how we got here

mukashiSep 30, 2021, 4:26 AM
14 points
0 comments8 min readLW link

2021 Dar­win Game—Contestants

lsusrOct 3, 2021, 5:09 AM
70 points
17 comments1 min readLW link

2021 Dar­win Game—Tundra

lsusrOct 5, 2021, 5:03 AM
48 points
17 comments2 min readLW link

[Book Re­view] “I Con­tain Mul­ti­tudes” by Ed Yong

J BostockOct 4, 2021, 7:29 PM
12 points
1 comment7 min readLW link

2021 Dar­win Game—Desert

lsusrOct 6, 2021, 12:24 AM
37 points
2 comments2 min readLW link

2021 Dar­win Game—Ocean

lsusrOct 6, 2021, 1:59 AM
27 points
2 comments4 min readLW link

2021 Dar­win Game—Benthic

lsusrOct 6, 2021, 4:39 AM
25 points
0 comments3 min readLW link

2021 Dar­win Game—Hu­man Garbage Dump

lsusrOct 6, 2021, 6:31 AM
36 points
7 comments4 min readLW link

2021 Dar­win Game—River

lsusrOct 6, 2021, 7:29 AM
30 points
8 comments1 min readLW link

2021 Dar­win Game—Every­where Else

lsusrOct 6, 2021, 8:39 PM
48 points
18 comments6 min readLW link

There aren’t enough smart peo­ple in biol­ogy do­ing some­thing boring

Abhishaike MahajanOct 21, 2024, 3:52 PM
27 points
13 comments10 min readLW link

[Book Re­view] “The Bell Curve” by Charles Murray

lsusrNov 2, 2021, 5:49 AM
94 points
134 comments23 min readLW link

Se­cond-or­der se­lec­tion against the immortal

MalmesburyDec 3, 2021, 5:01 AM
45 points
47 comments6 min readLW link

Are big brains for pro­cess­ing sen­sory in­put?

lsusrDec 10, 2021, 7:08 AM
42 points
20 comments3 min readLW link

I got dysen­tery so you don’t have to

eukaryoteOct 22, 2024, 4:55 AM
320 points
6 comments17 min readLW link
(eukaryotewritesblog.com)

Why in­door light­ing is hard to get right and how to fix it

Richard Korzekwa Oct 28, 2020, 4:46 AM
212 points
54 comments15 min readLW link1 review

Whence the sexes?

Richard_NgoFeb 13, 2022, 8:40 PM
61 points
35 comments3 min readLW link
(thinkingcomplete.blogspot.com)

Es­ti­mat­ing Brain-Equiv­a­lent Com­pute from Image Recog­ni­tion Al­gorithms

Gunnar_ZarnckeFeb 27, 2022, 2:45 AM
14 points
4 comments2 min readLW link

Scien­tific Wrestling: Beyond Pas­sive Hy­poth­e­sis-Testing

adamShimiMar 7, 2022, 12:01 PM
43 points
6 comments8 min readLW link

The­o­ries of Mo­du­lar­ity in the Biolog­i­cal Literature

Apr 4, 2022, 12:48 PM
51 points
13 comments7 min readLW link

I Caught Covid And All I Got Was This Lousy Am­bigu­ous Data

ElizabethApr 21, 2022, 7:30 PM
47 points
0 comments4 min readLW link
(acesounderglass.com)

It’s Prob­a­bly Not Lithium

NatáliaJun 28, 2022, 9:24 PM
442 points
187 comments28 min readLW link1 review

Seek­ing beta read­ers who are ig­no­rant of biol­ogy but knowl­edge­able about AI safety

Holly_ElmoreJul 27, 2022, 11:02 PM
11 points
6 comments1 min readLW link

Stone Age Her­bal­ist’s notes on ant war­fare and slavery

trevorNov 9, 2024, 2:40 AM
32 points
0 comments3 min readLW link
(x.com)

Gra­di­ent Hacker De­sign Prin­ci­ples From Biology

johnswentworthSep 1, 2022, 7:03 PM
60 points
13 comments3 min readLW link

Straight-edge Warn­ing Against Phys­i­cal Intimacy

RaphaëllNov 23, 2020, 9:35 PM
17 points
42 comments5 min readLW link

Se­quenc­ing In­tro II: Adapters

jefftkSep 15, 2022, 3:30 AM
12 points
0 comments2 min readLW link
(www.jefftk.com)

Gene drives: why the wait?

MetacelsusSep 19, 2022, 11:37 PM
125 points
50 comments3 min readLW link
(denovo.substack.com)

Orexin and the quest for more wak­ing hours

ChristianKlSep 24, 2022, 7:54 PM
131 points
39 comments5 min readLW link

Phoenix Rising

MetacelsusMar 9, 2025, 11:53 AM
66 points
7 comments5 min readLW link
(denovo.substack.com)

We Haven’t Uploaded Worms

jefftkDec 27, 2014, 11:44 AM
156 points
19 comments2 min readLW link

re: Yud­kowsky on biolog­i­cal materials

bhauthDec 11, 2023, 1:28 PM
182 points
30 comments5 min readLW link

In­sti­tu­tional eco­nomics through the lens of scale-free reg­u­la­tive de­vel­op­ment, mor­pho­gen­e­sis, and cog­ni­tive science

Roman LeventovJan 23, 2024, 7:42 PM
8 points
0 comments14 min readLW link

Meth­ods for strong hu­man germline en­g­ineer­ing

TsviBTMar 3, 2025, 8:13 AM
147 points
28 comments108 min readLW link

Co­or­di­na­tion Prob­lems in Evolu­tion: Ei­gen’s Paradox

Martin SustrikOct 12, 2018, 12:40 PM
105 points
6 comments8 min readLW link
(250bpm.com)

Mechanisms too sim­ple for hu­mans to design

MalmesburyJan 22, 2025, 4:54 PM
199 points
45 comments15 min readLW link

you should prob­a­bly eat oat­meal sometimes

bhauthAug 25, 2024, 2:50 PM
42 points
32 comments3 min readLW link
(bhauth.com)

On not get­ting con­tam­i­nated by the wrong obe­sity ideas

NatáliaJan 28, 2023, 8:18 PM
306 points
69 comments30 min readLW link

Pan­demic Pre­dic­tion Check­list: H5N1 (6/​14)

DirectedEvolutionFeb 5, 2023, 3:26 AM
50 points
10 comments7 min readLW link

Why Are Bac­te­ria So Sim­ple?

aysjaFeb 6, 2023, 3:00 AM
172 points
33 comments10 min readLW link

What’s Be­hind the SynBio Bust?

sarahconstantinJan 30, 2025, 10:30 PM
55 points
8 comments6 min readLW link
(sarahconstantin.substack.com)

The Cancer Re­s­olu­tion?

PeterMcCluskeyJul 24, 2024, 12:25 AM
34 points
27 comments6 min readLW link
(bayesianinvestor.com)

Fun With The Tab­ula Muris (Se­nis)

sarahconstantinSep 20, 2024, 6:20 PM
25 points
0 comments8 min readLW link
(sarahconstantin.substack.com)

Moder­ately Skep­ti­cal of “Risks of Mir­ror Biol­ogy”

DavidmanheimDec 20, 2024, 12:57 PM
32 points
3 comments9 min readLW link
(substack.com)

Twiblings, four-par­ent ba­bies and other re­pro­duc­tive technology

GeneSmithMay 20, 2023, 5:11 PM
191 points
33 comments6 min readLW link

Coron­avirus Virol­ogy: A Begin­ner’s Guide

brookMar 28, 2020, 8:47 PM
25 points
7 comments5 min readLW link

How bad is chlo­ri­nated wa­ter?

bhauthDec 13, 2023, 6:00 PM
43 points
18 comments3 min readLW link
(www.bhauth.com)

Seek­ing sug­ges­tions: Less Wrong Biol­ogy 101

virtualAdeptMay 20, 2011, 3:28 PM
46 points
22 comments1 min readLW link

Papers on pro­tein design

alexlyzhovMay 27, 2023, 1:18 AM
9 points
0 comments3 min readLW link

in defense of Linus Pauling

bhauthJun 3, 2024, 9:27 PM
49 points
8 comments2 min readLW link
(www.bhauth.com)

[Question] Why didn’t vi­rol­o­gists run the stud­ies nec­es­sary to de­ter­mine which viruses are air­borne?

ChristianKlJun 20, 2023, 11:58 AM
28 points
19 comments1 min readLW link

shoes with springs

bhauthDec 30, 2023, 9:46 PM
69 points
9 comments4 min readLW link2 reviews
(www.bhauth.com)

$250 prize for check­ing Jake Can­nell’s Brain Efficiency

Alexander Gietelink OldenzielApr 26, 2023, 4:21 PM
123 points
170 comments2 min readLW link

Re­con­sider the anti-cav­ity bac­te­ria if you are Asian

Lao MeinApr 15, 2024, 7:02 AM
169 points
43 comments4 min readLW link

What is a Se­quenc­ing Read?

jefftkOct 25, 2023, 2:10 AM
17 points
2 comments2 min readLW link
(www.jefftk.com)

The Case for Hu­man Ge­netic Engineering

GeneSmithAug 28, 2020, 10:21 PM
51 points
19 comments12 min readLW link

Evolu­tion of Modularity

johnswentworthNov 14, 2019, 6:49 AM
185 points
12 comments2 min readLW link1 review

[Question] Could we breed/​en­g­ineer in­tel­li­gent par­rots?

lemonhopeAug 2, 2023, 7:32 AM
9 points
18 comments1 min readLW link

The Great­est Host

trentbrickMay 10, 2020, 8:28 PM
33 points
8 comments14 min readLW link

on bac­te­ria, on teeth

bhauthSep 30, 2024, 3:56 PM
62 points
9 comments6 min readLW link
(bhauth.com)

Le­gal­ize bu­tanol?

bhauthDec 20, 2023, 2:24 PM
39 points
20 comments5 min readLW link
(www.bhauth.com)

Op­ti­cal Illu­sions are Out of Distri­bu­tion Errors

vitaliyaAug 15, 2023, 2:23 AM
30 points
8 comments2 min readLW link

Aaron Silver­book on anti-cav­ity bacteria

DanielFilanNov 20, 2023, 3:06 AM
31 points
3 comments1 min readLW link
(youtu.be)

in­tro­duc­tion to can­cer vaccines

bhauthMay 5, 2024, 1:06 AM
113 points
19 comments5 min readLW link
(www.bhauth.com)

Se­quenc­ing Intro

jefftkAug 29, 2022, 5:50 PM
39 points
3 comments5 min readLW link
(www.jefftk.com)

Do bam­boos set them­selves on fire?

MalmesburySep 19, 2022, 3:34 PM
170 points
14 comments6 min readLW link1 review

[Question] Does biol­ogy re­li­ably find the global max­i­mum, or at least get close?

Noosphere89Oct 10, 2022, 8:55 PM
24 points
71 comments1 min readLW link

What is epi­ge­net­ics?

MetacelsusNov 6, 2022, 1:24 AM
78 points
4 comments6 min readLW link
(denovo.substack.com)

The limited up­side of interpretability

Peter S. ParkNov 15, 2022, 6:46 PM
13 points
11 comments1 min readLW link

Un­pack­ing “Shard The­ory” as Hunch, Ques­tion, The­ory, and Insight

Jacy Reese AnthisNov 16, 2022, 1:54 PM
31 points
9 comments2 min readLW link

Epi­ge­net­ics of the mam­malian germline

MetacelsusDec 23, 2022, 3:21 PM
37 points
0 comments7 min readLW link
(denovo.substack.com)

Build­ing a tran­shu­man­ist fu­ture: 15 years of hplus­roadmap, now Discord

kanzureJan 17, 2023, 9:17 PM
42 points
1 comment1 min readLW link
(twitter.com)

Bioin­for­mat­ics 101

iy3dJan 22, 2023, 2:36 AM
5 points
0 comments4 min readLW link

Why I’m Skep­ti­cal of De-Extinction

Niko_McCartyFeb 23, 2023, 7:42 PM
16 points
1 comment11 min readLW link
(cell.substack.com)

The Ogdoad

Tristan MianoMar 5, 2023, 8:01 PM
−15 points
1 comment37 min readLW link

[Question] Has Eliezer ever re­tracted his state­ments about weight loss?

CheerfulWarriorOct 14, 2020, 7:04 PM
−14 points
32 comments1 min readLW link

The Limits of Ar­tifi­cial Con­scious­ness: A Biol­ogy-Based Cri­tique of Chalmers’ Fad­ing Qualia Argument

Štěpán LosDec 17, 2023, 7:11 PM
−6 points
9 comments17 min readLW link

Smart peo­ple should do biology

HaotianDec 5, 2024, 7:11 PM
11 points
2 comments3 min readLW link

AI’s im­pact on biol­ogy re­search: Part I, today

octopoctaDec 23, 2023, 4:29 PM
31 points
6 comments2 min readLW link

A primer on why com­pu­ta­tional pre­dic­tive tox­i­col­ogy is hard

Abhishaike MahajanAug 19, 2024, 5:16 PM
63 points
2 comments12 min readLW link
(www.owlposting.com)

Ap­ply to the 2024 PIBBSS Sum­mer Re­search Fellowship

Jan 12, 2024, 4:06 AM
39 points
1 comment2 min readLW link

A primer on the cur­rent state of longevity research

Abhishaike MahajanAug 22, 2024, 5:14 PM
109 points
6 comments14 min readLW link
(www.owlposting.com)

Can AI im­prove the cur­rent state of molec­u­lar simu­la­tion?

Abhishaike MahajanDec 6, 2024, 8:22 PM
5 points
0 comments1 min readLW link
(www.owlposting.com)

Day Zero An­tivirals for Fu­ture Pandemics

Niko_McCartyAug 26, 2024, 3:18 PM
22 points
2 comments10 min readLW link
(www.asimov.press)

Things I learned talk­ing to the new breed of sci­en­tific institution

Abhishaike MahajanAug 29, 2024, 2:00 PM
42 points
6 comments14 min readLW link
(www.owlposting.com)

[Question] How to ac­cel­er­ate re­cov­ery from sleep debt with bio­hack­ing?

exanovaApr 10, 2024, 1:27 AM
10 points
2 comments1 min readLW link

A primer on the next gen­er­a­tion of antibodies

Abhishaike MahajanSep 1, 2024, 10:37 PM
25 points
0 comments19 min readLW link
(www.owlposting.com)

[Question] Why don’t we just get rid of all the bioethi­cists?

SableJun 8, 2024, 3:48 AM
13 points
0 comments1 min readLW link

The Dangers of Mir­rored Life

Dec 12, 2024, 8:58 PM
119 points
8 comments29 min readLW link
(www.asimov.press)

Fic­tional par­a­sites very differ­ent from our own

Abhishaike MahajanSep 8, 2024, 2:59 PM
25 points
0 comments4 min readLW link
(www.owlposting.com)

I’m a bit skep­ti­cal of AlphaFold 3

Oleg TrottJun 25, 2024, 12:04 AM
87 points
14 comments2 min readLW link

Sex, Death, and Complexity

Zero ContradictionsJul 25, 2024, 9:22 PM
0 points
0 comments1 min readLW link
(thewaywardaxolotl.blogspot.com)

Can o1-pre­view find ma­jor mis­takes amongst 59 NeurIPS ’24 MLSB pa­pers?

Abhishaike MahajanDec 18, 2024, 2:21 PM
19 points
0 comments6 min readLW link
(www.owlposting.com)

Gen­er­a­tive ML in chem­istry is bot­tle­necked by synthesis

Abhishaike MahajanSep 16, 2024, 4:31 PM
38 points
2 comments14 min readLW link
(www.owlposting.com)

Longevity: A crit­i­cal look at “Loss of epi­ge­netic in­for­ma­tion as a cause of mam­malian ag­ing”

Anna CrowJul 24, 2024, 1:40 AM
14 points
2 comments10 min readLW link

A primer on ma­chine learn­ing in cryo-elec­tron microscopy (cryo-EM)

Abhishaike MahajanDec 22, 2024, 3:11 PM
18 points
0 comments25 min readLW link
(www.owlposting.com)

Mak­ing Eggs Without Ovaries

Sep 22, 2024, 5:44 PM
58 points
3 comments16 min readLW link
(www.asimov.press)

A primer on ML in an­ti­body engineering

Abhishaike MahajanSep 23, 2024, 5:03 PM
11 points
0 comments25 min readLW link
(www.owlposting.com)

Models of life

Abhishaike MahajanSep 29, 2024, 7:24 PM
8 points
0 comments16 min readLW link
(www.asimov.press)

To Be Born in a Bag

Niko_McCartyOct 6, 2024, 5:21 PM
19 points
1 comment16 min readLW link
(www.asimov.press)

Su­per hu­man AI is a very low hang­ing fruit!

HznDec 26, 2024, 7:00 PM
−4 points
0 comments7 min readLW link

The un­rea­son­able effec­tive­ness of plas­mid se­quenc­ing as a service

Abhishaike MahajanOct 8, 2024, 2:02 AM
23 points
2 comments13 min readLW link
(www.owlposting.com)

Pat­terns or get­ting to Ob­jec­tive Truth – A thought piece on Ar­tifi­cial Intelligence

Thehumanproject.aiOct 20, 2024, 4:45 PM
1 point
0 comments8 min readLW link

Pat­terns or get­ting to Ob­jec­tive Truth – A thought piece on Ar­tifi­cial Intelligence

Thehumanproject.aiOct 20, 2024, 4:45 PM
1 point
0 comments8 min readLW link

NAO Up­dates, Fall 2024

jefftkOct 18, 2024, 12:00 AM
32 points
2 comments1 min readLW link
(naobservatory.org)

Lev­ers for Biolog­i­cal Progress—A Re­sponse to “Machines of Lov­ing Grace”

Niko_McCartyNov 1, 2024, 4:35 PM
15 points
0 comments20 min readLW link
(www.asimov.press)

Why Re­cur­sion Phar­ma­ceu­ti­cals aban­doned cell paint­ing for bright­field imaging

Abhishaike MahajanNov 5, 2024, 2:51 PM
29 points
1 comment18 min readLW link
(www.owlposting.com)

Ge­net­i­cally ed­ited mosquitoes haven’t scaled yet. Why?

alexeyDec 30, 2024, 9:37 PM
24 points
0 comments1 min readLW link
(eryney.substack.com)

My Ex­pe­rience With A Mag­net Implant

ValeJan 7, 2025, 3:01 AM
9 points
2 comments1 min readLW link
(vale.rocks)

Why mod­el­ling multi-ob­jec­tive home­osta­sis is es­sen­tial for AI al­ign­ment (and how it helps with AI safety as well)

Roland PihlakasJan 12, 2025, 3:37 AM
46 points
7 comments10 min readLW link

Bet­ter an­ti­bod­ies by en­g­ineer­ing tar­gets, not en­g­ineer­ing an­ti­bod­ies (Nabla Bio)

Abhishaike MahajanJan 13, 2025, 3:05 PM
4 points
0 comments14 min readLW link
(www.owlposting.com)

Is there such a thing as an im­pos­si­ble pro­tein?

Abhishaike MahajanJan 24, 2025, 5:12 PM
15 points
3 comments4 min readLW link
(www.owlposting.com)

Notable run­away-op­ti­miser-like LLM failure modes on Biolog­i­cally and Eco­nom­i­cally al­igned AI safety bench­marks for LLMs with sim­plified ob­ser­va­tion format

Mar 16, 2025, 11:23 PM
36 points
6 comments7 min readLW link

The Univer­sal Lock­pick Hy­poth­e­sis: A Struc­tural Vuln­er­a­bil­ity of All Life

Cole HolinMar 23, 2025, 7:27 PM
1 point
0 comments2 min readLW link

Cor­rect­ing a mis­con­cep­tion: con­scious­ness does not need 90 billion neu­rons, at all

bvbvbvbvbvbvbvbvbvbvbvMar 31, 2023, 4:02 PM
21 points
19 comments1 min readLW link

My ex­pe­rience get­ting fund­ing for my biolog­i­cal research

MetacelsusApr 16, 2023, 10:53 PM
77 points
10 comments5 min readLW link
(denovo.substack.com)

Green goo is plausible

anithiteApr 18, 2023, 12:04 AM
62 points
31 comments4 min readLW link1 review

Wastew­a­ter RNA Read Lengths

jefftkNov 10, 2023, 3:20 PM
13 points
0 comments4 min readLW link
(www.jefftk.com)

The dan­gers of re­pro­duc­ing while old

garymmNov 17, 2023, 5:55 AM
23 points
6 comments1 min readLW link
(www.garymm.org)

Paper out now on cre­a­tine and cog­ni­tive performance

FabienneNov 26, 2023, 10:58 AM
59 points
2 comments1 min readLW link

Black Box Biology

GeneSmithNov 29, 2023, 2:27 AM
65 points
30 comments2 min readLW link

A call for a quan­ti­ta­tive re­port card for AI bioter­ror­ism threat models

JunoDec 4, 2023, 6:35 AM
12 points
0 comments10 min readLW link

[Question] Are par­a­sitic worms an effec­tive weapon against MS?

DemeterJul 23, 2020, 1:59 PM
31 points
11 comments9 min readLW link

Are AIs like An­i­mals? Per­spec­tives and Strate­gies from Biology

Jackson EmanuelMay 16, 2023, 11:39 PM
1 point
0 comments21 min readLW link

His­tor­i­cal math­e­mat­i­ci­ans ex­hibit a birth or­der effect too

Eli TyreAug 21, 2018, 1:52 AM
146 points
20 comments6 min readLW link2 reviews

Can the Chain Still Hold You?

lukeprogJan 13, 2012, 1:28 AM
215 points
361 comments4 min readLW link

He­donic asymmetries

paulfchristianoJan 26, 2020, 2:10 AM
98 points
22 comments2 min readLW link
(sideways-view.com)

In­tro­duc­ing the Longevity Re­search Institute

sarahconstantinDec 14, 2018, 8:20 PM
79 points
11 comments1 min readLW link
(srconstantin.wordpress.com)

Bioinfohazards

SpiracularSep 17, 2019, 2:41 AM
87 points
14 comments18 min readLW link2 reviews

Zetetic explanation

BenquoAug 27, 2018, 12:12 AM
95 points
138 comments6 min readLW link
(benjaminrosshoffman.com)

Ex­pe­riences in ap­ply­ing “The Biode­ter­minist’s Guide to Par­ent­ing”

juliawiseJul 17, 2015, 7:19 PM
124 points
34 comments9 min readLW link

Global in­sect de­clines: Why aren’t we all dead yet?

eukaryoteApr 1, 2018, 8:38 PM
28 points
26 comments1 min readLW link

Refram­ing the evolu­tion­ary benefit of sex

paulfchristianoSep 14, 2019, 5:00 PM
92 points
21 comments2 min readLW link
(sideways-view.com)

Notes From an Apocalypse

ToggleSep 22, 2017, 5:10 AM
59 points
24 comments14 min readLW link

How spe­cial are hu­man brains among an­i­mal brains?

zhukeepaApr 1, 2020, 1:35 AM
79 points
38 comments7 min readLW link

The E-Coli Test for AI Alignment

johnswentworthDec 16, 2018, 8:10 AM
70 points
24 comments1 min readLW link

Might hu­mans not be the most in­tel­li­gent an­i­mals?

Matthew BarnettDec 23, 2019, 9:50 PM
56 points
41 comments3 min readLW link

What is up with car­bon diox­ide and cog­ni­tion? An offer

paulfchristianoApr 23, 2016, 5:47 PM
84 points
48 comments2 min readLW link

Cephaloponderings

Jacob FalkovichAug 4, 2019, 4:45 PM
39 points
4 comments7 min readLW link

Bio­di­ver­sity for heretics

eukaryoteMay 27, 2018, 1:37 PM
14 points
4 comments7 min readLW link

[Question] How Old is Smal­lpox?

RaemonDec 10, 2018, 10:50 AM
44 points
5 comments2 min readLW link

Solv­ing sleep: just a toe-dipping

CaplaJun 30, 2015, 7:38 PM
63 points
34 comments4 min readLW link

Be­ware of Stephen J. Gould

Eliezer YudkowskyNov 6, 2007, 5:22 AM
60 points
80 comments6 min readLW link

What Uni­parental Di­somy Tells Us About Im­proper Im­print­ing in Humans

MorpheusMar 28, 2025, 11:24 AM
22 points
1 comment6 min readLW link

Group se­lec­tion update

PhilGoetzNov 1, 2010, 4:51 PM
49 points
68 comments5 min readLW link

[Question] Ap­pli­ca­tions of Eco­nomic Models to Phys­iol­ogy?

johnswentworthDec 10, 2019, 6:09 PM
38 points
22 comments1 min readLW link

[Question] Why do hu­mans not have built-in neu­ral i/​o chan­nels?

Richard_NgoAug 8, 2019, 1:09 PM
25 points
23 comments1 min readLW link

Biosafety Reg­u­la­tions (BMBL) and their rele­vance for AI

Štěpán LosJun 29, 2023, 7:22 PM
4 points
0 comments4 min readLW link

SRG 4: Biolog­i­cal Cog­ni­tion, BCIs, Organizations

KatjaGraceOct 7, 2014, 1:00 AM
14 points
139 comments5 min readLW link

“Con­cepts of Agency in Biol­ogy” (Okasha, 2023) - Brief Paper Summary

Nora_AmmannJul 8, 2023, 6:22 PM
40 points
3 comments7 min readLW link

Refram­ing Evolu­tion—An in­for­ma­tion wavefront trav­el­ing through time

Joshua ClancyJul 10, 2023, 10:36 PM
1 point
0 comments5 min readLW link
(midflip.org)

Ar­tifi­cial In­tel­li­gence and Life Sciences (Why Big Data is not enough to cap­ture biolog­i­cal sys­tems?)

HansNaujJan 15, 2020, 1:59 AM
6 points
3 comments6 min readLW link

More Ques­tions about Trees

digital_carverOct 9, 2020, 8:35 AM
3 points
5 comments1 min readLW link
(bit-player.org)

Cel­lu­lar res­pi­ra­tion as a steam engine

dkl9Feb 25, 2024, 8:17 PM
24 points
1 comment1 min readLW link
(dkl9.net)

Now is the time to elimi­nate mosquitoes

James_MillerAug 6, 2016, 7:10 PM
33 points
89 comments1 min readLW link

An In­tro­duc­tion to Me

AlithyInfinityAug 24, 2023, 4:45 PM
0 points
0 comments2 min readLW link

In­vad­ing Aus­tralia (End­less Former­lies Most Beau­tiful, or What I Learned On My Holi­day)

Oliver SourbutSep 8, 2023, 3:33 PM
12 points
1 comment8 min readLW link
(www.oliversourbut.net)

In­hi­bi­tion and the Mind

AnnoyanceMay 21, 2009, 5:34 PM
10 points
29 comments2 min readLW link

Ho­mo­gene­ity vs. het­ero­gene­ity (or, What kind of sex is most moral?)

PhilGoetzMay 22, 2009, 11:25 PM
−6 points
79 comments2 min readLW link

[Linkpost] AlphaFold: a solu­tion to a 50-year-old grand challenge in biology

adamShimiNov 30, 2020, 5:33 PM
54 points
22 comments1 min readLW link
(deepmind.com)

Will no one rid me of this tur­bu­lent pest?

MetacelsusOct 14, 2023, 3:27 PM
154 points
23 comments10 min readLW link
(denovo.substack.com)

Germs and Poli­tics

Savio CoelhoMar 1, 2021, 9:57 PM
1 point
1 comment10 min readLW link

Notes on “Bioter­ror and Biowar­fare” (2006)

MichaelAMar 2, 2021, 12:43 AM
10 points
3 comments4 min readLW link

Will Mar­tian G be enough to make healthy baseline ba­bies?

Randomized, ControlledMar 9, 2021, 3:30 AM
4 points
8 comments1 min readLW link

Biolog­i­cal Holism: A New Paradigm?

WaddingtonMay 9, 2021, 10:42 PM
4 points
9 comments19 min readLW link

Al­co­hol, health, and the ruth­less logic of the Asian flush

dynomightJun 4, 2021, 6:14 PM
149 points
45 comments1 min readLW link
(dynomight.net)

Quan­tum par­ti­cles and clas­si­cal filaments

From_Branes_to_BrainsSep 4, 2021, 9:45 PM
11 points
5 comments4 min readLW link

Elephant seal 2

KatjaGraceFeb 2, 2021, 9:40 AM
60 points
8 comments1 min readLW link2 reviews
(worldspiritsockpuppet.com)

Ac­ti­vated Char­coal for Han­gover Preven­tion: Way more than you wanted to know

Maxwell PetersonJan 10, 2022, 7:26 PM
86 points
31 comments31 min readLW link1 review

Na­ture’s an­swer to the ex­plore/​ex­ploit problem

lizard_brainApr 8, 2022, 5:13 AM
5 points
1 comment1 min readLW link

A Brief Ex­cur­sion Into Molec­u­lar Neuroscience

JanApr 10, 2022, 5:55 PM
48 points
8 comments19 min readLW link
(universalprior.substack.com)
No comments.