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Hu­man Genetics

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A Brief Re­view of Cur­rent and Near-Fu­ture Meth­ods of Ge­netic Engineering

GeneSmithApr 10, 2021, 7:16 PM
82 points
33 comments15 min readLW link

Is ge­net­ics “dark”?

David Hugh-JonesNov 1, 2021, 6:23 PM
42 points
12 comments5 min readLW link
(wyclif.substack.com)

[Question] What is the cur­rent bot­tle­neck on ge­netic en­g­ineer­ing of hu­man em­bryos for im­proved IQ

Eli TyreOct 23, 2020, 2:36 AM
36 points
13 comments1 min readLW link

(Book Re­view) The Ge­netic Lot­tery: Why DNA Mat­ters for So­cial Equality

XylitolOct 7, 2021, 10:21 PM
25 points
11 comments17 min readLW link

Su­perba­bies: Put­ting The Pie­ces Together

sarahconstantinJul 11, 2024, 8:40 PM
215 points
37 comments10 min readLW link
(sarahconstantin.substack.com)

The Case for Hu­man Ge­netic Engineering

GeneSmithAug 28, 2020, 10:21 PM
51 points
19 comments12 min readLW link

Sig­nifi­cantly En­hanc­ing Adult In­tel­li­gence With Gene Edit­ing May Be Possible

Dec 12, 2023, 6:14 PM
452 points
206 comments33 min readLW link2 reviews

How to Make Superbabies

Feb 19, 2025, 8:39 PM
556 points
326 comments31 min readLW link

Why Selec­tive Breed­ing is a Bad Way to do Ge­netic Engineering

GeneSmithMar 5, 2021, 2:30 AM
12 points
14 comments2 min readLW link

can­cer rates af­ter gene therapy

bhauthOct 16, 2024, 3:32 PM
53 points
2 comments3 min readLW link
(bhauth.com)

Twiblings, four-par­ent ba­bies and other re­pro­duc­tive technology

GeneSmithMay 20, 2023, 5:11 PM
191 points
33 comments6 min readLW link

His­tor­i­cal math­e­mat­i­ci­ans ex­hibit a birth or­der effect too

Eli TyreAug 21, 2018, 1:52 AM
146 points
20 comments6 min readLW link2 reviews

Her­i­ta­bil­ity: Five Battles

Steven ByrnesJan 14, 2025, 6:21 PM
76 points
21 comments60 min readLW link

Meth­ods for strong hu­man germline en­g­ineer­ing

TsviBTMar 3, 2025, 8:13 AM
146 points
27 comments108 min readLW link

Tran­shu­man­ism, ge­netic en­g­ineer­ing, and the biolog­i­cal ba­sis of in­tel­li­gence.

fowlertmSep 14, 2022, 3:55 PM
41 points
23 comments1 min readLW link

Re­ply to a fer­til­ity doc­tor con­cern­ing poly­genic em­bryo screening

GeneSmithMay 29, 2023, 9:50 PM
59 points
6 comments8 min readLW link

Re­view of “Make Peo­ple Bet­ter”

MetacelsusJan 2, 2023, 8:30 PM
10 points
0 comments3 min readLW link
(denovo.substack.com)

Up­date on Chi­nese IQ-re­lated gene panels

Lao MeinDec 14, 2023, 10:12 AM
70 points
7 comments1 min readLW link

A gen­eral com­ment on dis­cus­sions of ge­netic group differences

anonymous8101Jan 14, 2023, 2:11 AM
70 points
46 comments3 min readLW link

Q&A with Harpend­ing and Cochran

MBlumeMay 10, 2010, 11:01 PM
34 points
112 comments1 min readLW link

Jour­nal ar­ti­cle: “The Myth­i­cal Ta­boo on Race and In­tel­li­gence”

CronoDASOct 16, 2020, 2:58 AM
−17 points
11 comments1 min readLW link
(journals.sagepub.com)

A Book Review

Zack_M_DavisApr 28, 2020, 5:43 PM
15 points
3 comments1 min readLW link
(unremediatedgender.space)

The Atomic Bomb Con­sid­ered As Hun­gar­ian High School Science Fair Project

Scott AlexanderMay 26, 2017, 9:45 AM
56 points
10 comments14 min readLW link

Eu­gen­ics Performed By A Blind, Idiot God

omnizoidSep 17, 2023, 8:37 PM
63 points
11 comments2 min readLW link

The Psy­cholog­i­cal Diver­sity of Mankind

Kaj_SotalaMay 9, 2010, 5:53 AM
144 points
162 comments7 min readLW link

Con­struct­ing fic­tional eu­gen­ics (LW edi­tion)

Eliezer YudkowskyOct 29, 2012, 12:41 AM
30 points
175 comments4 min readLW link

Your genome isn’t pri­vate. Maybe it never was.

epiphiSep 19, 2018, 8:22 PM
15 points
0 comments1 min readLW link
(www.eastbaybiosecurity.org)

The vir­tu­ous cir­cle: twelve con­jec­tures about fe­male re­pro­duc­tive agency and cul­tural self-determination

Miles SaltielDec 27, 2023, 6:25 PM
0 points
2 comments14 min readLW link

Five toy wor­lds to think about her­i­ta­bil­ity

David Hugh-JonesJun 28, 2024, 1:11 PM
13 points
0 comments9 min readLW link
(wyclif.substack.com)

The Math­e­mat­i­cal Rea­son You should have 9 Kids

Zero ContradictionsJan 16, 2025, 11:24 AM
−9 points
6 comments1 min readLW link
(eternalanglo.com)

Are we the Wolves now? Hu­man Eu­gen­ics un­der AI Control

BritJan 30, 2025, 8:31 AM
−2 points
1 comment2 min readLW link

6. The Mutable Values Prob­lem in Value Learn­ing and CEV

RogerDearnaleyDec 4, 2023, 6:31 PM
12 points
0 comments49 min readLW link

Ge­nomic Pre­dic­tion is now offer­ing em­bryo selection

gwernOct 7, 2018, 9:27 PM
38 points
1 comment1 min readLW link
(genomicprediction.com)

How to have Poly­geni­cally Screened Children

GeneSmithMay 7, 2023, 4:01 PM
365 points
128 comments27 min readLW link1 review

Ge­net­i­cally Mod­ified Hu­mans Born (Allegedly)

ryan_bNov 28, 2018, 4:14 PM
29 points
12 comments1 min readLW link

Get geno­typed for free ( If your IQ is high enough)

David AlthausOct 1, 2011, 4:00 PM
49 points
63 comments1 min readLW link

In­ter­pret­ing ge­netic testing

jefftkDec 15, 2018, 3:56 PM
24 points
1 comment2 min readLW link

[Re­quest]: Use “Epi­lo­gen­ics” in­stead of “Eu­gen­ics” in most circumstances

GeneSmithJun 1, 2023, 3:36 PM
56 points
49 comments1 min readLW link

Thoughts on min­i­miz­ing de­signer baby drama

John_MaxwellMay 12, 2015, 11:22 AM
26 points
195 comments2 min readLW link

[Question] What are the risks of hav­ing your genome pub­li­cly available?

Mati_RoyFeb 11, 2020, 9:54 PM
16 points
13 comments1 min readLW link

What could be done with RNA and DNA se­quenc­ing that’s 1000x cheaper than it’s now?

ChristianKlJun 26, 2018, 12:24 PM
16 points
7 comments1 min readLW link

Albion’s Seed, Genotyped

Scott AlexanderFeb 9, 2017, 2:15 AM
17 points
0 comments2 min readLW link

Hu­man Ge­netic Eng­ineer­ing: In­creas­ing Intelligence

GeneSmithDec 5, 2020, 10:06 PM
37 points
5 comments10 min readLW link

Core Path­ways of Aging

johnswentworthMar 28, 2021, 12:31 AM
274 points
129 comments22 min readLW link1 review

The Ge­net­ics of Space Ama­zons

Jan Christian RefsgaardDec 30, 2021, 10:14 PM
12 points
12 comments5 min readLW link

Tak­ing Clones Seriously

Raymond DDec 1, 2021, 5:29 PM
56 points
45 comments2 min readLW link

Ge­net­ics: It some­times skips a gen­er­a­tion is a ter­rible ex­pla­na­tion!

Jan Christian RefsgaardJan 1, 2022, 3:12 PM
15 points
10 comments1 min readLW link