The resting VO2 will need to be post-processed to be a diagnostic indicator. A brief look indicates that it is a function of sex (higher in men), age (higher in younger people), and weight. Might be a function of physical fitness (or at least lean body mass) as well.
Yes, sorry, thank you. The important quantity would be metabolic rate divided by the best prediction from the known relevant variables, as you say. It was once a test for hypothyroidism, so whatever the last word pre-blood test was should be good enough.
As I say, Broda Barnes found this test wanting and preferred waking axillary temperature (for females, on the correct days; for males, anytime), but it should be plenty good enough to establish that there’s something funny going on. The problem is to draw the attention of medical science to it at all. I trust them to sort out the details.
The problem is to draw the attention of medical science to it at all.
You are digging into this problem and I suspect there’s enough published data on RMR (resting metabolic rate) in healthy and not-so-healthy people to collate some interesting evidence.
Agree, we should be able to refute it or strongly support it from the published literature. My initial attempts at that look like refutation. How can fibromyalgia in Turkish women be associated with HIGHER body temperature if my hypotheses are true?
And I wonder if there are enough Less Wrong readers with friends with these diseases to make a survey of some sort?
The resting VO2 will need to be post-processed to be a diagnostic indicator. A brief look indicates that it is a function of sex (higher in men), age (higher in younger people), and weight. Might be a function of physical fitness (or at least lean body mass) as well.
Yes, sorry, thank you. The important quantity would be metabolic rate divided by the best prediction from the known relevant variables, as you say. It was once a test for hypothyroidism, so whatever the last word pre-blood test was should be good enough.
As I say, Broda Barnes found this test wanting and preferred waking axillary temperature (for females, on the correct days; for males, anytime), but it should be plenty good enough to establish that there’s something funny going on. The problem is to draw the attention of medical science to it at all. I trust them to sort out the details.
You are digging into this problem and I suspect there’s enough published data on RMR (resting metabolic rate) in healthy and not-so-healthy people to collate some interesting evidence.
Agree, we should be able to refute it or strongly support it from the published literature. My initial attempts at that look like refutation. How can fibromyalgia in Turkish women be associated with HIGHER body temperature if my hypotheses are true?
And I wonder if there are enough Less Wrong readers with friends with these diseases to make a survey of some sort?
That’s not how you find patients a lot of patients. It makes more sense to seek online communitites where people with the illnesses congregate.
There’s the patientslikeme forum: https://www.patientslikeme.com/forum/fibromyalgia/topics
http://www.fibromyalgiaforums.org/
http://www.healingwell.com/community/?f=24