I strongly think cancer research has a huge space and can’t think of anything more difficult within biology.
I was being careless / unreflective about the size of the cancer solution space, by splitting the solution spaces of alignment and cancer differently; nor do I know enough about cancer to make such claims. I split the space into immunotherapies, things which target epigenetics / stem cells, and “other”, where in retrospect the latter probably has the optimal solution. This groups many small problems with possibly weakly-general solutions into a “bottleneck”, as you mentioned:
aging may be a general factor to many diseases, but research into many of the things aging relates to is composed of solving many small problems that do not directly relate to aging, and defining solving aging as a bottleneck problem and judging generalizability with respect to it doesn’t seem useful.
Later:
Define the baseline distribution generalizability is defined on.
For a given problem, generalizability is how likely a given sub-solution is to be part of the final solution, assuming you solve the whole problem. You might choose to model expected utility, if that differs between full solutions; I chose not to here because I natively separate generality from power.
Give a little intuition about why a threshold is meaningful, rather than a linear “more general is better”.
I agree that “more general is better” with a linear or slightly superlinear (because you can make plans which rely heavier on solution) association with success probability. We were already making different value statements about “weakly” vs “strongly” general, where putting concrete probabilities / ranges might reveal us to agree w.r.t the baseline distribution of generalizability and disagree only on semantics.
I.e. thresholds are only useful for communication.
Perhaps a better way to frame this is in ratios of tractability (how hard to identify and solve) and usefulness (conditional on the solution working) between solutions with different levels generalizability. E.g. suppose some solution is 5x less general than . Then you expect, for the types of problems and solutions humans encounter, that will be more than 5x as tractable * useful as .
I disagree in expectation, meaning for now I target most of my search at general solutions.
My model of the central AIS problems:
How to make some AI do what we want? (under immense functionally adversarial pressures)
Why does the AI do things? (Abstractions / context-dependent heuristics; how do agents split reality given assumptions about training / architecture)
How do we change those things-which-cause-AI-behavior?
How do we use behavior specification to maximize our lightcone?
How to actually get technical alignment into a capable AI? (AI labs / governments)
What do we want the AI to do? (“Long reflection” / CEV / other)
I’d be extremely interested to hear anyone’s take on my model of the central problems.
How much would you say (3) supports (1) on your model? I’m still pretty new to AIS and am updating from your model.
I agree that marginal improvements are good for fields like medicine, and perhaps so too AIS. E.g. I can imagine self-other overlap scaling to near-ASI, though I’m doubtful about stability under reflection. I’ll put 35% we find a semi-robust solution sufficient to not kill everyone.
I think that the distribution of success probability of typical optimal-from-our-perspective solutions is very wide for both of the ways we describe generalizability; within that, we should weight generalizability heavier than my understanding of your model does.
Earlier:
Is this saying people should coordinate in case valuable solutions aren’t in the apriori generalizable space?