Acquiring the substance may be simpler than I thought. This thread contains an interesting discussion with an apparent chemist about how to have the polypeptide custom-made, in some countries (e.g. Norway) it’s not even patented (yet?). Apparently you can order at some of the same places the researchers order their stuff from, complete with mass spec data as verification, at comparatively low prices—certainly lower than what the official drug will sell for.
at comparatively low prices—certainly lower than what the official drug will sell for.
Lower? Really? That’s surprising. All the previous discussions of custom synthesis sources I had encountered had prohibitive pricing due to lack of economics of scale. ie $6,000 for a cycle.
I’d be very surprised if the patent holder sold a full cycle for $6k or less. Antibodies (think cancer drugs) aren’t on the order of magnitude as expensive to produce as they’re sold for, either. Patients will pay whatever they can if the non-human primate results transfer to humans.
Acquiring the substance may be simpler than I thought. This thread contains an interesting discussion with an apparent chemist about how to have the polypeptide custom-made, in some countries (e.g. Norway) it’s not even patented (yet?). Apparently you can order at some of the same places the researchers order their stuff from, complete with mass spec data as verification, at comparatively low prices—certainly lower than what the official drug will sell for.
Lower? Really? That’s surprising. All the previous discussions of custom synthesis sources I had encountered had prohibitive pricing due to lack of economics of scale. ie $6,000 for a cycle.
I’d be very surprised if the patent holder sold a full cycle for $6k or less. Antibodies (think cancer drugs) aren’t on the order of magnitude as expensive to produce as they’re sold for, either. Patients will pay whatever they can if the non-human primate results transfer to humans.