As an example, look at E484K—this mutation changes the amino acid polarity, so that antibodies trained against the E variant will have a much harder time attaching to the K variant. If an antibody fails to attach, it doesn’t ‘crowd out’ anything.
That makes sense; I was wondering about this exact thing. It seems like VB is painting a worst-case scenario where a bunch of things go wrong in a specific way. Perhaps not impossible, but based on what you’re saying, there’s no reason to be unusually concerned.
That makes sense; I was wondering about this exact thing. It seems like VB is painting a worst-case scenario where a bunch of things go wrong in a specific way. Perhaps not impossible, but based on what you’re saying, there’s no reason to be unusually concerned.