Really hard to know without more research on the subject.
My subjective impression from working with mice and rats is that there isn’t a strong negative reaction to having bits of their cortex stimulated in various ways (electrodes, optogenetics).
Unlike, say, experiments where we test their startle reaction by placing them in a small cage with a motion sensor and then playing a loud startling sound. They hate that!
Really hard to know without more research on the subject.
My subjective impression from working with mice and rats is that there isn’t a strong negative reaction to having bits of their cortex stimulated in various ways (electrodes, optogenetics).
Unlike, say, experiments where we test their startle reaction by placing them in a small cage with a motion sensor and then playing a loud startling sound. They hate that!