Yes, it’s important to build a strong foundation before establishing firm opinions. Also, in this particular case note that science appears to have recently changed it’s mind based on further evidence, which goes to show that you have to be careful when reading wikipedia. Apparently the protein in question is not so likely to underlie LTM after all, as transgenic mice lacking it still have LTM (exhibiting maze memory, LTP, etc). The erasure of memory is linked to zeta inhibitory peptide (ZIP), which incidentally happens in the transgenic mice as well.
ETA: Apparently PKMzeta can be used to restore faded memories erased with ZIP.
Yes, it’s important to build a strong foundation before establishing firm opinions. Also, in this particular case note that science appears to have recently changed it’s mind based on further evidence, which goes to show that you have to be careful when reading wikipedia. Apparently the protein in question is not so likely to underlie LTM after all, as transgenic mice lacking it still have LTM (exhibiting maze memory, LTP, etc). The erasure of memory is linked to zeta inhibitory peptide (ZIP), which incidentally happens in the transgenic mice as well.
ETA: Apparently PKMzeta can be used to restore faded memories erased with ZIP.