[Link] Evidence of Fabricated Data in a Vitamin C trial by Paul E Marik et al in CHEST

[Kenny]

Link:

• This Scattrd Corn: Evidence of Fabricated Data in a Vitamin C trial by Paul E Marik et al in CHEST

The trial paper:

• Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock—CHEST

The trial, and funding it, were discussed first (that I remember) about five years ago:

• Sepsis Cure Needs An RCT | Otium

• An Opportunity to Throw Money at the Problem of Medical Science – Aceso Under Glass

• Update on Sepsis: Donations Probably Unnecessary | Otium

[Kenny]

There’s some mentions of the trial in the comments on this otherwise unrelated post:

• “When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?” | Statistical Modeling, Causal Inference, and Social Science