Trial and error? E.g. first you upload animal subjects and see what’s fidelity seems to preserve all the animal traits you can find. At some point you then start with human volunteers (perhaps preferentially dying people?), and see whether the rates that seem to work for nonhuman animals also work for humans.
Also I guess once you have a mostly-working human upload, you can test perturbations to this upload to see what factors they are most sensitive to.
Trial and error? E.g. first you upload animal subjects and see what’s fidelity seems to preserve all the animal traits you can find. At some point you then start with human volunteers (perhaps preferentially dying people?), and see whether the rates that seem to work for nonhuman animals also work for humans.
Also I guess once you have a mostly-working human upload, you can test perturbations to this upload to see what factors they are most sensitive to.