This is a shotgun comment, and sorry if I’m being very ignorant here (I’ve stopped following most covid science-y stuff in the last year+), but:
The evidence for ivermectin, while poor, is about as reasonable as that for any repurposed covid drug (e.g. fluvoxamine), and even purpose-made ones (plaxovid) [emphasis mine]
Aren’t the effects of Paxlovid pretty extreme?
In studies, mortality benefits large enough (>10x?) it really slams you in the face.
My understanding is that in 2022, covid mortality has gotten lower in the general population, even among unvaccinated people.
My understanding is that you don’t have effects nearly this large and well-studied for ivermectin on covid. If anything (feel free to correct me!) countries that use ivermectin a lot have pretty high covid mortality, though of course there are many confounders.
Given that this was my claim and not the author’s I’d rather not discuss it since I’d detract from the point.
But tl;dr, strength aside, if you count all trials ivm efficacy is arguably higher than plaxovid, once you start eliminating and de-biasing the story changes, the direction and magnitude of change is the whole story that generated e.g. Scott’s ivm post and this reply.
This is a shotgun comment, and sorry if I’m being very ignorant here (I’ve stopped following most covid science-y stuff in the last year+), but:
Aren’t the effects of Paxlovid pretty extreme?
In studies, mortality benefits large enough (>10x?) it really slams you in the face.
My understanding is that in 2022, covid mortality has gotten lower in the general population, even among unvaccinated people.
My understanding is that you don’t have effects nearly this large and well-studied for ivermectin on covid. If anything (feel free to correct me!) countries that use ivermectin a lot have pretty high covid mortality, though of course there are many confounders.
Given that this was my claim and not the author’s I’d rather not discuss it since I’d detract from the point.
But tl;dr, strength aside, if you count all trials ivm efficacy is arguably higher than plaxovid, once you start eliminating and de-biasing the story changes, the direction and magnitude of change is the whole story that generated e.g. Scott’s ivm post and this reply.