Several dozen people now presumably have Lumina in their mouths. Can we not simply crowdsource some assays of their saliva? I would chip money in to this. Key questions around ethanol levels, aldehyde levels, antibacterial levels, and whether the organism itself stays colonized at useful levels.
Lumina is incredibly cheap right now. I pre-ordered for 250usd. Even genuinely quite poor people I know don’t find the price off-putting (poor in the sense of absolutely poor for the country they live in). I have never met a single person who decided not to try Lumina because the price was high. If they pass its always because they think its risky.
I think Romeo is thinking of checking a bunch of mediators of risk (like aldehyde levels) as well as of function (like whether the organism stays colonised)
Maybe I’m late to the conversation but has anyone thought through what happens when Lumina colonizes the mouths of other people? Mouth bacteria is important for things like conversation of nitrate to nitrite for nitric oxide production. How do we know the lactic acid metabolism isn’t important or Lumina won’t outcompete other strains important for overall health?
Any recommendations on how I should do that? You may assume that I know what a gas chromatograph is and what a Petri dish is and why you might want to use either or both of those for data collection, but not that I have any idea of how to most cost-effectively access either one as some rando who doesn’t even have a MA in Chemistry.
Several dozen people now presumably have Lumina in their mouths. Can we not simply crowdsource some assays of their saliva? I would chip money in to this. Key questions around ethanol levels, aldehyde levels, antibacterial levels, and whether the organism itself stays colonized at useful levels.
Lumina is incredibly cheap right now. I pre-ordered for 250usd. Even genuinely quite poor people I know don’t find the price off-putting (poor in the sense of absolutely poor for the country they live in). I have never met a single person who decided not to try Lumina because the price was high. If they pass its always because they think its risky.
I think Romeo is thinking of checking a bunch of mediators of risk (like aldehyde levels) as well as of function (like whether the organism stays colonised)
Maybe I’m late to the conversation but has anyone thought through what happens when Lumina colonizes the mouths of other people? Mouth bacteria is important for things like conversation of nitrate to nitrite for nitric oxide production. How do we know the lactic acid metabolism isn’t important or Lumina won’t outcompete other strains important for overall health?
Surely so! Hit me up if you ever end doing this—I’m likely getting the Lumina treatment in a couple months.
A before and after would be even better!
Any recommendations on how I should do that? You may assume that I know what a gas chromatograph is and what a Petri dish is and why you might want to use either or both of those for data collection, but not that I have any idea of how to most cost-effectively access either one as some rando who doesn’t even have a MA in Chemistry.