For clarification, would you consider an amino acid sequence designed to have a certain function to pass this test? For example, a sequence that generates a protein capable of binding selectively to specific RNA sequences?
Good question. I had been thinking of it differently, where the user inputs a 3D shape and the AI outputs an amino acid sequence that codes a protein of that shape. But perhaps it would be even more useful to have the inputs be functions, as you say. E.g. “Give me a protein that has two ends, one of which binds selectively to the SARS-COV-2 virus, and the other of which signals the immune system to attack.” It wasn’t what I had in mind though.
Yup, that would be another good example. I would guess that sequences designed for functions like these will be developed faster than sequences designed for shape, because the incentives to do so already exist. If you generate a gear or axle, what could you do with it? Are there known applications for such things? Ultimately we could imagine molecular machines made of such a toolkit, but that seems like another level of complexity. (Although perhaps it could tie in with work along the lines of Fraser Stoddart’s group.)
For clarification, would you consider an amino acid sequence designed to have a certain function to pass this test? For example, a sequence that generates a protein capable of binding selectively to specific RNA sequences?
Good question. I had been thinking of it differently, where the user inputs a 3D shape and the AI outputs an amino acid sequence that codes a protein of that shape. But perhaps it would be even more useful to have the inputs be functions, as you say. E.g. “Give me a protein that has two ends, one of which binds selectively to the SARS-COV-2 virus, and the other of which signals the immune system to attack.” It wasn’t what I had in mind though.
Yup, that would be another good example. I would guess that sequences designed for functions like these will be developed faster than sequences designed for shape, because the incentives to do so already exist. If you generate a gear or axle, what could you do with it? Are there known applications for such things? Ultimately we could imagine molecular machines made of such a toolkit, but that seems like another level of complexity. (Although perhaps it could tie in with work along the lines of Fraser Stoddart’s group.)