Oh, ok, the mechanism is familiar to me and in hindsight this makes sense !
But then, my follow-up would be, if all you are doing is up/down-regulating certain proteins or regions encoding several proteins wouldn’t you be able to more easily either get the proteins or plasmids or RNAviruses expressing the proteins into the brain ? Which would be temporary but could be long lasting (and cheap) and would not pose this risk
Oh, ok, the mechanism is familiar to me and in hindsight this makes sense !
But then, my follow-up would be, if all you are doing is up/down-regulating certain proteins or regions encoding several proteins wouldn’t you be able to more easily either get the proteins or plasmids or RNAviruses expressing the proteins into the brain ? Which would be temporary but could be long lasting (and cheap) and would not pose this risk