Just to report data, I’ll repeat my comments about vitamin D that I put on Scott’s blogpost:
On Zvi’s advice, I took 4000 IU of Vitamin D per day for about 2 months.
Then I got kidney stones, and one of the doctors I chatted with said it could likely be from the Vitamin D, and I reasoned that I’d stored up enough Vitamin D (I think it gets stored in fats?) that I should stop taking it. Because having kidney stones was No Fun.
I did have a kidney stone 2 years ago, so it’s plausible that getting it again is independent. (Also plausible that the Vitamin D exacerbated it.)
Mild TMI medical info that is not important and is just bragging:
(Also, for all you redditors bragging about your amazingly large 4 millimeter stones, my stone was 8 millimeters.)
Did you take vitamin K? You really need that to process vitamin D. This LessWrong post goes into more detail. Quotes from the article:
Atli Arnarson makes the case in Is Vitamin D Harmful Without Vitamin K? that Vitamin D toxicity at high doses is usually about K2 deficiency because both are needed in the same pathways and more K2 is needed when there’s more Vitamin D. Vitamin D toxicity leads to hypercalcemia where there’s too much Calcium in the blood. Calcifediol moves some calcium from the bone to the blood and K2 is needed to put the calcium in the bones. Hypercalcemia is bad because it lead to blood vessel calcification. Observational studies link low Vitamin K2 levels to blood vessel calcification with K2 being more important than K1.
I don’t. Now that we have more visibility, people who know more, please say more.
This would potentially explain the disagreement—if taking lots of D requires K2 but no one’s testing with K2 then all the huge correlations would be there but the interventions wouldn’t work.
Thanks. It wasn’t that bad really. Mostly just wasted a lot of time. The most suffering was when I didn’t know what was causing the pain, because then I think about the worst things it could mean.
Just to report data, I’ll repeat my comments about vitamin D that I put on Scott’s blogpost:
Mild TMI medical info that is not important and is just bragging:
(Also, for all you redditors bragging about your amazingly large 4 millimeter stones, my stone was 8 millimeters.)
Did you take vitamin K? You really need that to process vitamin D. This LessWrong post goes into more detail. Quotes from the article:
I don’t. Now that we have more visibility, people who know more, please say more.
This would potentially explain the disagreement—if taking lots of D requires K2 but no one’s testing with K2 then all the huge correlations would be there but the interventions wouldn’t work.
I did not.
Wow I am sorry you had to go through that.
Thanks. It wasn’t that bad really. Mostly just wasted a lot of time. The most suffering was when I didn’t know what was causing the pain, because then I think about the worst things it could mean.