I know the causal closure of the physical as the principle that nothing non-physical influences physical stuff, so that would be the causal closure of the bottom level of description (since there is no level below the physical), rather than the upper.
So if you mean by that that it’s enough to simulate neurons rather than individual atoms, that wouldn’t be “causal closure” as Wikipedia calls it.
I know the causal closure of the physical as the principle that nothing non-physical influences physical stuff, so that would be the causal closure of the bottom level of description (since there is no level below the physical), rather than the upper.
So if you mean by that that it’s enough to simulate neurons rather than individual atoms, that wouldn’t be “causal closure” as Wikipedia calls it.