Qn: Could you clarify the intended audience and final use case for this research? It would help to choose between technical depth/accessibility/level of supporting info.
Mitisaks
Karma: 16
On the slight chance that it does end up improving life expectancy of big dogs prone to DCM because it reduces chances of death due to cardiomegaly, would this then be a cardiovascular drug and not a longevity drug? And are the endpoints anything related to cardiac health outcomes (EF/ heart size/others)?
An extension of the logic would be that all cardiac interventions are longevity interventions because heart diseases are the most common cause of death. That seems odd. Were COVID vaccines longevity interventions cz over time the restored the dip in average life span brought about by the pandemic? (This might just be me not understanding the distinctions around what makes a longevity drug in general; is the goal increasing life, increasing quality of life in later decades, or to reduce overall ageing process/wear and tear starting at a young point ie 40s in humans)
Thanks for posting this! Reading the post took me back to my med school days.
Cadaver lab has a bad reputation in medical school; almost everyone hates it. For me, the experience of learning anatomy could not have been complete without it. I attended medical school in India. We were assigned a cadaver among eight students for all of the first year, four students on each half. Fortunately, I shared my half with three other students who were not interested in ‘digging in,’ and I got almost half to myself! 17 yo, me, who joined med school to become a surgeon, was elated!
I love that as you narrate your experience, you highlight the curiosity of discovery. Your excitement with the process was palpable. Some of the most exciting anecdotes of my med school experience took place in the cadaver lab. Also, being in India, most of the approaches to cadaver labs were quite traditional. E.g., i can never forget the pungent stench of formalin (enough to cause teary eyes), mixed with a decaying stench that was characteristic of a cadaver lab. I could write on and on, but I don’t want to hijack your post.
If you plan to go again and want to chat about something, I’d be happy to have a call!
I will look into doing this if I ever move to the bay area. However, that would need a solid reason to justify my using a cadaver again. I don’t think recreational use is respectful as opposed to educational.
I am concerned that by removing pills from their original packaging (blister or pill box), you are losing track of the expiry date of the medications, putting you at risk of sub-optimal drug effects. Perhaps, also label the date by which you replace the meds?
Other random pointers (I am a medical doctor):
- I highly recommend Ondansetron. It should be easy to request any doctor you see to write you a prescription for one. It works like a charm for any nausea, hangover, migraine, seasickness, stomach bug, heartburn, or anxiety, etc.
- Acetaminophen(Tylenol) or Paracetamol, based on where you are located, is a must for fevers.
- If you are prone to allergies, carrying an antihistamine, such as cetirizine or levocetirizine, helps a lot.
- Saline eye drops for dryness (long hours at the computer), or random foreign bodies (specks)
- Add something for heartburn/acidity. This can be ranitidine or omeprazole(Id avoid this but for extreme cases) . This works when you eat something spicy or too much of something leading to discomfort. Look at this as a one-step above your regular tums.
- Personal fav pill organizer
Should I write a detailed post or link a detailed google doc about OTCs?
Here is some info about antivirals for H5N1, a collation of information that I find relevant, and details from a very recent paper that studied Baloxavir/Favipiravir: https://docs.google.com/document/d/17xa3bdaCgK1Sf3Xpt6WEnzkZbECgGsdFJStBZ67e648/edit?tab=t.0
What this does not include at the moment is information on resistance.