One UI for this I could imagine (for non-mobile wide-screen use) is to have the post and the comments appear in two columns with the post on the left and the comments on the right (Similar to the Mac OS X Finder’s column view.) Then when the user clicks on a comment the appropriate bit of the post would get highlighted.
In fact, I could see doing a similar thing for the individual comments themselves to create a view that would show the *ancestry* of a single comment, stretching left back to the post the conversation was originally about. This could save a fair amount of scrolling.
If you want to encourage engagement, don’t hide the new comment box all the way down at the bottom of the page! Put another one right after the post (or give the post a reply button of the same sort the comments have.)