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GeneSmith

Karma: 4,999

I’m a software developer by training with an interest in genetics. I currently run a startup working on multiplex gene editing technology.

How to Make Superbabies

GeneSmith and kman
Feb 19, 2025, 8:39 PM
565 points
327 comments31 min readLW link

Den­tistry, Oral Sur­geons, and the Ineffi­ciency of Small Markets

GeneSmithNov 1, 2024, 5:26 PM
84 points
16 comments5 min readLW link

GeneSmith’s Shortform

GeneSmithSep 7, 2024, 5:09 AM
4 points
26 comments1 min readLW link

Why you should be us­ing a retinoid

GeneSmithAug 19, 2024, 3:07 AM
98 points
60 comments5 min readLW link

Sig­nifi­cantly En­hanc­ing Adult In­tel­li­gence With Gene Edit­ing May Be Possible

GeneSmith and kman
Dec 12, 2023, 6:14 PM
453 points
206 comments33 min readLW link2 reviews

Black Box Biology

GeneSmithNov 29, 2023, 2:27 AM
65 points
30 comments2 min readLW link

Digi­tal brains beat biolog­i­cal ones be­cause diffu­sion is too slow

GeneSmithAug 26, 2023, 2:22 AM
78 points
21 comments5 min readLW link

[Question] How to take ad­van­age of the mar­ket’s ir­ra­tional­ity re­gard­ing AGI?

GeneSmithAug 16, 2023, 3:30 AM
24 points
7 comments2 min readLW link

[Re­quest]: Use “Epi­lo­gen­ics” in­stead of “Eu­gen­ics” in most circumstances

GeneSmithJun 1, 2023, 3:36 PM
56 points
49 comments1 min readLW link

Re­ply to a fer­til­ity doc­tor con­cern­ing poly­genic em­bryo screening

GeneSmithMay 29, 2023, 9:50 PM
59 points
6 comments8 min readLW link

Twiblings, four-par­ent ba­bies and other re­pro­duc­tive technology

GeneSmithMay 20, 2023, 5:11 PM
191 points
33 comments6 min readLW link

How to have Poly­geni­cally Screened Children

GeneSmithMay 7, 2023, 4:01 PM
365 points
128 comments27 min readLW link1 review

The de­fault out­come for al­igned AGI still looks pretty bad

GeneSmithMar 27, 2023, 12:02 AM
13 points
19 comments3 min readLW link

Ponzi schemes can be highly prof­itable if your timing is good

GeneSmithDec 12, 2022, 6:42 AM
10 points
18 comments5 min readLW link

Toni Kurz and the In­san­ity of Climb­ing Mountains

GeneSmithJul 3, 2022, 8:51 PM
271 points
67 comments11 min readLW link2 reviews

We need a stan­dard set of com­mu­nity ad­vice for how to fi­nan­cially pre­pare for AGI

GeneSmithJun 7, 2021, 7:24 AM
51 points
52 comments5 min readLW link

[Question] Es­ti­mat­ing COVID cases & deaths in In­dia over the com­ing months

GeneSmithApr 24, 2021, 9:35 PM
33 points
8 comments1 min readLW link

A Brief Re­view of Cur­rent and Near-Fu­ture Meth­ods of Ge­netic Engineering

GeneSmithApr 10, 2021, 7:16 PM
82 points
33 comments15 min readLW link

Why Selec­tive Breed­ing is a Bad Way to do Ge­netic Engineering

GeneSmithMar 5, 2021, 2:30 AM
13 points
14 comments2 min readLW link

Hu­man Ge­netic Eng­ineer­ing: In­creas­ing Intelligence

GeneSmithDec 5, 2020, 10:06 PM
37 points
5 comments10 min readLW link