I heard David Friedberg on the all-in podcast mention that he was pretty nervous about it because the drug messed with some pretty fundamental biological machinery…
Just heard that episode today and was thinking the samething. The scuttlebutt I’ve heard elsewhere is that paxlovid has several mechanisms to prevent viral replication. One of those mechanisms is similar to an HIV medication that has some known contraindications. OTOH HIV meds you take for life, Paxlovid you take for a few weeks. So my guess is that in the given the timespan you’re taking it, the risk is much lower.
Just heard that episode today and was thinking the samething. The scuttlebutt I’ve heard elsewhere is that paxlovid has several mechanisms to prevent viral replication. One of those mechanisms is similar to an HIV medication that has some known contraindications. OTOH HIV meds you take for life, Paxlovid you take for a few weeks. So my guess is that in the given the timespan you’re taking it, the risk is much lower.