report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide a new way to control the deadliest animal on Earth.
“What our compounds do is stop urine production, so they swell up and can’t volume regulate, and in some cases they just pop,” he said.
“By targeting blood feeding female mosquitoes, we predict that there will be less selective pressure for the emergence of resistant mutations,” Denton said.
The investigators show VU041 to be effective when applied topically, which indicates that it potentially could be adapted as a sprayed insecticide. They also show that it doesn’t harm honeybees.
report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide a new way to control the deadliest animal on Earth.
“What our compounds do is stop urine production, so they swell up and can’t volume regulate, and in some cases they just pop,” he said.
“By targeting blood feeding female mosquitoes, we predict that there will be less selective pressure for the emergence of resistant mutations,” Denton said.
The investigators show VU041 to be effective when applied topically, which indicates that it potentially could be adapted as a sprayed insecticide. They also show that it doesn’t harm honeybees.
https://www.eurekalert.org/pub_releases/2016-12/vumc-ei120516.php