Stories about transhumanism have to add downsides to make the story interesting.
You still have a choice between a maybe mortality is good after all aesop downside and, say, an infestation by an acausally emerging omnicidal sentient information payload downside.
You still have a choice between a maybe mortality is good after all aesop downside and, say, an infestation by an acausally emerging omnicidal sentient information payload downside.