That is largely what I’m getting from Sinclair’s Lifespan. What it seems to do, if I’m following his claim, is the restricted diet puts the body in a stressed mode (not malnourished state, that is to be avoided). The switches on come cellular activity that shift energy from cell division to cell maintenance and cleans up a lot of the garbage (malformed and miscoded proteins).
He also suggests that the other thing to diet wise it reduce the intake of some of the essential amino acids. We get too much of those and they are all associated with activating an enzyme that promotes the cellular division activities and away from the garbage collection and maintenance work.
I had not gotten to this point when asking the question but the book also goes on to say that a lot of different structures to the diet, each meal lite, fast a day a week or so, skip meals… all seem to function the same. Not surprising as all put us in a stressed mode and then the cell functions react. But he was not sure if some are perhaps better than others.
I don’t know if he has identified a gear, or or the as the book seems to suggest, for aging but interesting so far.
Thanks.
That is largely what I’m getting from Sinclair’s Lifespan. What it seems to do, if I’m following his claim, is the restricted diet puts the body in a stressed mode (not malnourished state, that is to be avoided). The switches on come cellular activity that shift energy from cell division to cell maintenance and cleans up a lot of the garbage (malformed and miscoded proteins).
He also suggests that the other thing to diet wise it reduce the intake of some of the essential amino acids. We get too much of those and they are all associated with activating an enzyme that promotes the cellular division activities and away from the garbage collection and maintenance work.
I had not gotten to this point when asking the question but the book also goes on to say that a lot of different structures to the diet, each meal lite, fast a day a week or so, skip meals… all seem to function the same. Not surprising as all put us in a stressed mode and then the cell functions react. But he was not sure if some are perhaps better than others.
I don’t know if he has identified a gear, or or the as the book seems to suggest, for aging but interesting so far.