Reading the original study, it seems like one problem is that even though leptin returned to normal, it was out of sync with resting metabolic rate, which meant appetite was no longer linked to energy requirements. There is some suggestion that a slower rate of weight loss might have more success in changing the set point, but that’s also contentious.
Sure.
Reading the original study, it seems like one problem is that even though leptin returned to normal, it was out of sync with resting metabolic rate, which meant appetite was no longer linked to energy requirements. There is some suggestion that a slower rate of weight loss might have more success in changing the set point, but that’s also contentious.