I’m not an immunologist so can’t talk of the efficacy of various vaccine strategies which seem unclear at the moment, but I ask myself—what is the opportunity cost of not getting a booster now? If we assume that omicron boosters will be available in (at best) 3-4 months, and then given to elderly or immunocompromised people first, the chance of me getting an omicron booster in the next 6 months is low. Weigh that against the chance of getting omicron covid in the next 6 months. Looking at the data, we can already establish that omicron is more contagious and looking at increases in infection rates in Europe over the last few weeks along with the fact that omicron will (probably) soon become the dominant strain, I’ll take a small increase in immunity now over a potentially larger one in 6 months when the omicron wave may be over. That’s just my risk calculation though—I got moderna booster yesterday. YMMV
The open hypothesis is that getting the booster against the alpha-spike-protein might increase the “original antigenic sin” dynamics and reduce the effect of the Omicron booster.
I’m not an immunologist so can’t talk of the efficacy of various vaccine strategies which seem unclear at the moment, but I ask myself—what is the opportunity cost of not getting a booster now? If we assume that omicron boosters will be available in (at best) 3-4 months, and then given to elderly or immunocompromised people first, the chance of me getting an omicron booster in the next 6 months is low. Weigh that against the chance of getting omicron covid in the next 6 months. Looking at the data, we can already establish that omicron is more contagious and looking at increases in infection rates in Europe over the last few weeks along with the fact that omicron will (probably) soon become the dominant strain, I’ll take a small increase in immunity now over a potentially larger one in 6 months when the omicron wave may be over. That’s just my risk calculation though—I got moderna booster yesterday. YMMV
The open hypothesis is that getting the booster against the alpha-spike-protein might increase the “original antigenic sin” dynamics and reduce the effect of the Omicron booster.