Pretty much all of those reasons—what it’s missing is that nicotine itself may also be a carcinogen- at least, it has the ability to be one: https://link.springer.com/article/10.1007/s10311-023-01668-1 Although there aren’t enough isolated studies done on nicotine in a long period to be conclusive: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020336/ Some reviews disagree: https://pubmed.ncbi.nlm.nih.gov/26380225/
Pretty much all of those reasons—what it’s missing is that nicotine itself may also be a carcinogen- at least, it has the ability to be one: https://link.springer.com/article/10.1007/s10311-023-01668-1
Although there aren’t enough isolated studies done on nicotine in a long period to be conclusive: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020336/
Some reviews disagree: https://pubmed.ncbi.nlm.nih.gov/26380225/