What mutually reinforcing factors would be maintaining people in a chronic fatigue equilibrium? I’d be fascinated if some chronic fatigue could be explained this way.
CFS features elevated inflammation, and some people argue is fundamentally a disease of inflammation.
Inflammation can be a bad equilibrium disease all on its own (two simple mechanisms: cytokines attract more immune cells, which themselves produce cytokines. The immune cells may additionally damage healthy tissue, which will produce more inflammation markers).
Inflammation leads to a panic mode where your body underinvests in itself long term.
Inflammation reduces ability to digest nutrients and raises sensitivity/allergies, so feeding yourself becomes harder.
This isn’t strictly biological and I wouldn’t call it BED on its own, but in practice anything that causes fatigue will make it harder to do things that help you in the long term.
Best guess, CFS is spurred by an initial infection, but lingers long after.
Something something mitochondria or energy thermostat something something.
What mutually reinforcing factors would be maintaining people in a chronic fatigue equilibrium? I’d be fascinated if some chronic fatigue could be explained this way.
CFS features elevated inflammation, and some people argue is fundamentally a disease of inflammation.
Inflammation can be a bad equilibrium disease all on its own (two simple mechanisms: cytokines attract more immune cells, which themselves produce cytokines. The immune cells may additionally damage healthy tissue, which will produce more inflammation markers).
Inflammation leads to a panic mode where your body underinvests in itself long term.
Inflammation reduces ability to digest nutrients and raises sensitivity/allergies, so feeding yourself becomes harder.
This isn’t strictly biological and I wouldn’t call it BED on its own, but in practice anything that causes fatigue will make it harder to do things that help you in the long term.
Best guess, CFS is spurred by an initial infection, but lingers long after.
Something something mitochondria or energy thermostat something something.