It appears that standard lab rats and mice are all morbidly obese. Using them as model organisms may give misleading results that fail to transfer to humans, or even to healthy rats and mice.
Does this reduce the whole calorie-restriction thing to nothing more than the advice to not be a fat slob? Well, maybe not, according to the author, but it has to make one wonder.
Another reason why a lot of studies may be wrong
It appears that standard lab rats and mice are all morbidly obese. Using them as model organisms may give misleading results that fail to transfer to humans, or even to healthy rats and mice.
Article in the Slate.
PNAS version.
Does this reduce the whole calorie-restriction thing to nothing more than the advice to not be a fat slob? Well, maybe not, according to the author, but it has to make one wonder.