Have I got the right link there? The post I found was just a reference to the difficulty of properly accounting for the placebo effect when drugs have obvious side effect profiles.
On that tangent active placebos can be fascinating. For example, studies investigating the effect of psyclobin which use ritalin as an active placebo (to match the euphoria experience).
Robin Hanson expands on the story a bit. My general impression is that the US has adopted a number of drugs which are worse on most dimensions than those that are deemed illegal partly due to a crappy system for approving chemicals.
I think the placebo effect is pretty interesting. I also think the powerful effect of many illegal psychoactive substances is pretty interesting. I find it unfortunate that the FDA has such a powerful role in deciding what constitutes legitimate investigation of either.
I’m not going to argue and say that the FDA system is good; but I’m happy that with a system as deeply flawed as the FDA that more deadly drugs don’t hit the market. Sure, lots of people die because there are working unapproved illegal treatments, but out of all of the unfortunate US government institutions, the FDA is not the worst.
Have I got the right link there? The post I found was just a reference to the difficulty of properly accounting for the placebo effect when drugs have obvious side effect profiles.
On that tangent active placebos can be fascinating. For example, studies investigating the effect of psyclobin which use ritalin as an active placebo (to match the euphoria experience).
Robin Hanson expands on the story a bit. My general impression is that the US has adopted a number of drugs which are worse on most dimensions than those that are deemed illegal partly due to a crappy system for approving chemicals.
I think the placebo effect is pretty interesting. I also think the powerful effect of many illegal psychoactive substances is pretty interesting. I find it unfortunate that the FDA has such a powerful role in deciding what constitutes legitimate investigation of either.
I’m not going to argue and say that the FDA system is good; but I’m happy that with a system as deeply flawed as the FDA that more deadly drugs don’t hit the market. Sure, lots of people die because there are working unapproved illegal treatments, but out of all of the unfortunate US government institutions, the FDA is not the worst.