CellBioGuy comments on Does BioNtech’s vaccine result of 90% disease prevention mean that 90% of the vaccinated can’t pass the virus to other people?

[CellBioGuy]

This being said, the challenge the monkeys were given was a massive dose of virus that is probably a good deal more than a human is ever likely to see. Also, you can have replication without having as much competent virus, especially if free virions are being neutralized via antibodies.