Brendan Long comments on Testing ChatGPT for cell type recognition

[Brendan Long]

I realized after asking that my default prompt makes ChatGPT really verbose so I changed the prompt to:

Identify types of human cells using the following marker genes. Identify one cell type for each row. Only provide the cell type name and no other commentary.

And it gave me:

1. Embryonic stem cells

2. Induced pluripotent stem cells

3. Endoderm

4. Granulosa cells

5. Oocytes

6. Pituitary gland cells

7. Germ cells

8. Leydig cells

9. Neurons

10. Meiotic cells

11. Sertoli cells

12. Neural progenitor cells

For 9 it’s actually interesting that if I let it give commentary it says:

CASC3, PGAP1, SLC6A16, CNTNAP4, NPHP1 - This set of genes does not point to a well-defined cell type but could suggest Neuronal Cells or specific types of Neural Precursors based on the presence of neural development and function genes.