Does that assume that the amount of mutations (and therefore the risk of an immune escape) is only dependent on the size of the viriome?
But isn’t it possible that the risk of an immune escape mutation in the 1-dose vaccinated population is much higher than in the rest of the population? I think if that was much higher, it could swamp the benefit of reduced overall chance for dangerous mutations occurring due to the reduced infections from vaccinating more people (as compared to 2 doses).
Not sure of any of this, just trying to think through your intuition.
Does that assume that the amount of mutations (and therefore the risk of an immune escape) is only dependent on the size of the viriome? But isn’t it possible that the risk of an immune escape mutation in the 1-dose vaccinated population is much higher than in the rest of the population? I think if that was much higher, it could swamp the benefit of reduced overall chance for dangerous mutations occurring due to the reduced infections from vaccinating more people (as compared to 2 doses). Not sure of any of this, just trying to think through your intuition.