Thanks for digging into the data! I agree that the rational response should be if you are predisposed to a problem to actively address the problem. But I still think a common response would be one of fatalism and stress. Have you looked into other potential sources of the nocebo effect? Maybe people being misdiagnosed with diseases that they don’t actually have?
From a quick look on Wikipedia I don’t see anything. Except for patients that report side effects from placebo, but of course that could be symptoms that they would have had in any case, which they incorrectly attribute to the placebo.
I don’t see how you could get an accurate measure of a nocebo effect from misdiagnoses. I don’t think anyone is willing to randomize patients to be misdiagnosed. And if you try to do it observationally, you run into the problem of distinguishing the effects of the misdiagnosis from whatever brought them to the doctor seeking diagnosis.
Thanks for digging into the data! I agree that the rational response should be if you are predisposed to a problem to actively address the problem. But I still think a common response would be one of fatalism and stress. Have you looked into other potential sources of the nocebo effect? Maybe people being misdiagnosed with diseases that they don’t actually have?
From a quick look on Wikipedia I don’t see anything. Except for patients that report side effects from placebo, but of course that could be symptoms that they would have had in any case, which they incorrectly attribute to the placebo.
I don’t see how you could get an accurate measure of a nocebo effect from misdiagnoses. I don’t think anyone is willing to randomize patients to be misdiagnosed. And if you try to do it observationally, you run into the problem of distinguishing the effects of the misdiagnosis from whatever brought them to the doctor seeking diagnosis.