To be clear, the work I am speaking of is on enhancing the NAD salvage pathway preventing NAD depletion in stressed neurons. This treatment seems to drastically decrease neuron programmed cell death in response to brain injury, neurodegenerative diseases, and hypoxia.
The mose work showed great promise in brain injury and hypoxia and while it doesn’t stop the neurodegeneration from ALS and the like (the underlying damage is being done) the threshold for individual neurons dying is raised, so the mice are healthy for a long time before suddenly falling apart rather than slowly declining.
This is work being done by Calico and by Dr. McKnight. I will provide links when I’m no longer on my phone
I did not know that… I can’t spare many neurons, I’d better check it out.
To be clear, the work I am speaking of is on enhancing the NAD salvage pathway preventing NAD depletion in stressed neurons. This treatment seems to drastically decrease neuron programmed cell death in response to brain injury, neurodegenerative diseases, and hypoxia.
The mose work showed great promise in brain injury and hypoxia and while it doesn’t stop the neurodegeneration from ALS and the like (the underlying damage is being done) the threshold for individual neurons dying is raised, so the mice are healthy for a long time before suddenly falling apart rather than slowly declining.
This is work being done by Calico and by Dr. McKnight. I will provide links when I’m no longer on my phone
Thanks!