I expect other pressures have changed, too. The first thing that comes to mind is that bitterness in plants is often a marker of toxicity; one of the steps in this quick and dirty edibity test for wild plants, for example, discards bitter ones. If a particular gene variant made a few harmless plants unpalatable but also made accidental poisonings less likely, I can see it being a net positive to foragers.
In an agricultural setting, where a few known-good plants make up most of the regular diet, the opposite might be true.
Modern vegetables are new on evolutionary timescales, because they’ve been bred for size. There may not have been time for human evolution to react.
I expect other pressures have changed, too. The first thing that comes to mind is that bitterness in plants is often a marker of toxicity; one of the steps in this quick and dirty edibity test for wild plants, for example, discards bitter ones. If a particular gene variant made a few harmless plants unpalatable but also made accidental poisonings less likely, I can see it being a net positive to foragers.
In an agricultural setting, where a few known-good plants make up most of the regular diet, the opposite might be true.