My understanding is that as of now we know waaay too little about the gut microbiome to make this “direct search in microbiome composition” viable. For example, we basically have no clue about bacteriophages in the gut. Yet they probably play an important role in gut health, and in the efficacy of FMTs.
Also, even if we knew exactly what composition we wanted, we aren’t very good yet to “synthesize it”/grow it in the lab.
My understanding is that as of now we know waaay too little about the gut microbiome to make this “direct search in microbiome composition” viable. For example, we basically have no clue about bacteriophages in the gut. Yet they probably play an important role in gut health, and in the efficacy of FMTs.
Also, even if we knew exactly what composition we wanted, we aren’t very good yet to “synthesize it”/grow it in the lab.