I think the inverse is even more striking: the Sinclair Method for treating alcoholism consists of the alcoholic just continuing to drink as before, but taking an opiod antagonist one hour before drinking. Before reading this article that just seemed like black magic to me, but it makes perfect sense once you know that neurons will become less connected if they fire together in the absence of dopamine.
I think the inverse is even more striking: the Sinclair Method for treating alcoholism consists of the alcoholic just continuing to drink as before, but taking an opiod antagonist one hour before drinking. Before reading this article that just seemed like black magic to me, but it makes perfect sense once you know that neurons will become less connected if they fire together in the absence of dopamine.