It feels to me like the general pro-cryo advocacy here would be a bit of a double standard, at least when compared to general memes of effective altruism, shutting up and multiplying, and saving the world. If I value my life equally to the lives of others, it seems pretty obvious that there’s no way by which the money spent on cryonics would be a better investment than spending it on general do-gooding.
I think the scale on which it is done is the main thing here. Currently, cryonics is performed so infrequently that there isn’t much infrastructure for it. So it is still fairly expensive compared to the amount of expected utility—probably close to the value implied by regulatory tradeoffs ($5 million per life). On a large, industrial scale I expect it to be far better value than anything Givewell is going to find.
This is good argument capable of convincing me into pro-cryonics position, if and only if someone can follow this claim by an evidence pointing to high probability estimate that preservation and restoration will become possible during a resonable time period.
If it so happens, that cryopreservation fails to prevent information-theoretic death then value of your cryo-magazines filled with with corpses will amount to exactly 0$ (unless you also preserve the organs for transplants).
This is good argument capable of convincing me into pro-cryonics position, if and only if someone can follow this claim by an evidence pointing to high probability estimate that preservation and restoration will become possible during a resonable time period.
At some point, you will have to specialize in cryobiology and neuroscience (with some information science in there too) in order to process the data. I can understand wanting to see the data for yourself, but expecting everyone to process it rationally and in depth before they get on board isn’t necessarily realistic for a large movement. Brian Wowk has written a lot of good papers on the challenges and mechanisms of cryopreservation, including cryoprotectant toxicity. Definitely worth reading up on. Even if you don’t decide to be pro-cryonics, you could use a lot of the information to support something related, like cryopreservation of organs.
If it so happens, that cryopreservation fails to prevent information-theoretic death then value of your cryo-magazines filled with with corpses will amount to exactly 0$ (unless you also preserve the organs for transplants).
Until you have enough information to know, with very high confidence, that information-theoretic death has happened in the best cases, you can’t really assign it all a $0 value in advance. You could perhaps assign a lower value than the cost of the project, but you would have to have enough information to do so justifiably. Ignorance cuts both ways here, and cryonics has traditionally been presented as an exercise in decision-making under conditions of uncertainty. I don’t see a reason that logic would change if there are millions of patients under consideration. (Although it does imply more people with an interest in resolving the question one way or another, if possible.)
I don’t quite agree that the value would be zero if it failed. It would probably displace various end-of-life medical and funeral options that are net-harmful, reduce religious fundamentalism, and increase investment in reanimation-relevant science (regenerative medicine, programmable nanodevices, etc). It would be interesting to see a comprehensive analysis of the positive and negative effects of cryonics becoming more popular. More organs for transplantation could be one effect worth accounting for, since it does not seem likely that we will need our original organs for reanimation. There would certainly be more pressure towards assisted suicide, so that could be positive or negative depending how you look at it.
I think the scale on which it is done is the main thing here. Currently, cryonics is performed so infrequently that there isn’t much infrastructure for it. So it is still fairly expensive compared to the amount of expected utility—probably close to the value implied by regulatory tradeoffs ($5 million per life). On a large, industrial scale I expect it to be far better value than anything Givewell is going to find.
This is good argument capable of convincing me into pro-cryonics position, if and only if someone can follow this claim by an evidence pointing to high probability estimate that preservation and restoration will become possible during a resonable time period.
If it so happens, that cryopreservation fails to prevent information-theoretic death then value of your cryo-magazines filled with with corpses will amount to exactly 0$ (unless you also preserve the organs for transplants).
At some point, you will have to specialize in cryobiology and neuroscience (with some information science in there too) in order to process the data. I can understand wanting to see the data for yourself, but expecting everyone to process it rationally and in depth before they get on board isn’t necessarily realistic for a large movement. Brian Wowk has written a lot of good papers on the challenges and mechanisms of cryopreservation, including cryoprotectant toxicity. Definitely worth reading up on. Even if you don’t decide to be pro-cryonics, you could use a lot of the information to support something related, like cryopreservation of organs.
Until you have enough information to know, with very high confidence, that information-theoretic death has happened in the best cases, you can’t really assign it all a $0 value in advance. You could perhaps assign a lower value than the cost of the project, but you would have to have enough information to do so justifiably. Ignorance cuts both ways here, and cryonics has traditionally been presented as an exercise in decision-making under conditions of uncertainty. I don’t see a reason that logic would change if there are millions of patients under consideration. (Although it does imply more people with an interest in resolving the question one way or another, if possible.)
I don’t quite agree that the value would be zero if it failed. It would probably displace various end-of-life medical and funeral options that are net-harmful, reduce religious fundamentalism, and increase investment in reanimation-relevant science (regenerative medicine, programmable nanodevices, etc). It would be interesting to see a comprehensive analysis of the positive and negative effects of cryonics becoming more popular. More organs for transplantation could be one effect worth accounting for, since it does not seem likely that we will need our original organs for reanimation. There would certainly be more pressure towards assisted suicide, so that could be positive or negative depending how you look at it.