This seems important and I’m a little surprised no one’s asked. How will her brain damage impact her chances of revival? (From the blog linked in the reddit post, it sounds like she is already experiencing symptoms.) Obviously she is quite mentally competent right now, but what about when she is declared legally dead? I am far from an expert and simply would like to hear some authoritative commentary on this. I am interested in donating but only if there’s a reasonable chance brain damage won’t make it superfluous.
Jim Glennie (A-1367) had a glioblastoma multiforme, and cryoprotective perfusion achieved the best Glycerol concentration at the time (6.02M glycerol, 1992). A-2091 (name withheld) also had a glioblastoma and reportedly “target cryoprotectant concentration was reached in the brain”.
Thomas Donaldson (A-1097) had an astrocytoma (I guess Astrocytes are a kind of glial cell, but I doubt the comparison can be extended further) and his cryopreservation was very good [p.16].
I am far from an expert and simply would like to hear some authoritative commentary on this
Disclaimer: I am not medically trained.
EDIT: I’m not sure if you’re referring to brain damage affecting cryoprotection or brain damage affecting her mental state and making her opt out.
What about the brain damage her tumor is causing?
This seems important and I’m a little surprised no one’s asked. How will her brain damage impact her chances of revival? (From the blog linked in the reddit post, it sounds like she is already experiencing symptoms.) Obviously she is quite mentally competent right now, but what about when she is declared legally dead? I am far from an expert and simply would like to hear some authoritative commentary on this. I am interested in donating but only if there’s a reasonable chance brain damage won’t make it superfluous.
Jim Glennie (A-1367) had a glioblastoma multiforme, and cryoprotective perfusion achieved the best Glycerol concentration at the time (6.02M glycerol, 1992). A-2091 (name withheld) also had a glioblastoma and reportedly “target cryoprotectant concentration was reached in the brain”.
Thomas Donaldson (A-1097) had an astrocytoma (I guess Astrocytes are a kind of glial cell, but I doubt the comparison can be extended further) and his cryopreservation was very good [p.16].
Disclaimer: I am not medically trained.
EDIT: I’m not sure if you’re referring to brain damage affecting cryoprotection or brain damage affecting her mental state and making her opt out.
I was mainly worried that she would suffer information-theoretic death (or substantial degradation) before she could be cryopreserved.
It is in her brainstem. Which while that makes it very difficult to treat, it probably increases her chances of being revived intact.