Do you (or others) have a sense of whether it’d be better to take Moderna or J&J after two doses of Pfizer? (Or whether to take Pfizer vs. J&J after two doses of Moderna)
No, but I would like to know. The two relevant variables are that mRNA is more effective, which we can sort of quantify, but non-mRNA is probably more different, which I don’t know how to quantify. Currently I view them as roughly equivalent, but an even cursory glance at what was in the mRNA vaccines vs non would potentially be quite helpful.
I have a tentative answer! Some cursory googling makes me think that J&J also just replicates the spike protein in you, the same way Pfizer/Moderna do. This means it’s just strictly less effective. Then you’d want to just do the Pfizer/Moderna one that you haven’t yet—unless Elizabeth’s comment about limited mRNA vaccine doses is decision-relevant, which I still haven’t looked into.
Do you (or others) have a sense of whether it’d be better to take Moderna or J&J after two doses of Pfizer? (Or whether to take Pfizer vs. J&J after two doses of Moderna)
No, but I would like to know. The two relevant variables are that mRNA is more effective, which we can sort of quantify, but non-mRNA is probably more different, which I don’t know how to quantify. Currently I view them as roughly equivalent, but an even cursory glance at what was in the mRNA vaccines vs non would potentially be quite helpful.
I have a tentative answer! Some cursory googling makes me think that J&J also just replicates the spike protein in you, the same way Pfizer/Moderna do. This means it’s just strictly less effective. Then you’d want to just do the Pfizer/Moderna one that you haven’t yet—unless Elizabeth’s comment about limited mRNA vaccine doses is decision-relevant, which I still haven’t looked into.