This is actually not relevant as warfarin dosage is determined by regular testing and dose adjustment. Your inborn metabolic rate is a very small effect compared to, for example, dietary preferences. (for those who are unfamiliar with the agent, warfarin antagonises the effects of vitamin K and so must be adjusted against dietary intake)
Unfortunately there are many people in the health sector offering tests that, whilst factually correct, are irrelevant to a patient’s care.
The influence of the genotype varies from “typical sensitivity” to “may require greatly decreased warfarin dose”. A range that is all but irrelevant, regular testing or no (think for example of the initial dosage).
Of note, 23andme tests for genetically determined warfarin tolerance. I can copypasta their references on demand.
This is actually not relevant as warfarin dosage is determined by regular testing and dose adjustment. Your inborn metabolic rate is a very small effect compared to, for example, dietary preferences. (for those who are unfamiliar with the agent, warfarin antagonises the effects of vitamin K and so must be adjusted against dietary intake)
Unfortunately there are many people in the health sector offering tests that, whilst factually correct, are irrelevant to a patient’s care.
Someone tell the NHS, which is sponsoring a large trial to explore just that question.
The influence of the genotype varies from “typical sensitivity” to “may require greatly decreased warfarin dose”. A range that is all but irrelevant, regular testing or no (think for example of the initial dosage).