I’ve already seen work to the effect that somatic cells often have ~10x the point mutations per human generation as the germline, which is protected by a small number of divisions per generation and low levels of metabolism and transcription. It was in mitochondrial rather than nuclear DNA, but the idea is similar.
I’ve already seen work to the effect that somatic cells often have ~10x the point mutations per human generation as the germline, which is protected by a small number of divisions per generation and low levels of metabolism and transcription. It was in mitochondrial rather than nuclear DNA, but the idea is similar.