1939, Nobel Prize-winning physicist Niels Bohr had argued that building an atomic bomb “can never be done unless you turn the United States into one huge factory.” Years later, he told his colleague Edward Teller, “I told you it couldn’t be done without turning the whole country into a factory. You have done just that.”
SImilar story is told about fission weaponry.
http://energy.gov/em/about-us/em-history