Having an overarching model (or several competing models) of which different parts can be tested independently seems like a structure which is very amenable towards different scientists, so I am disappointed none of the biological/medical community has started doing something like this.
This is actually done, quite a lot in fact, it’s just really hard and the search space is huge. Kudos to you for your analysis; it’s unlikely to be a major step forward, but given that idea search space is effectively exponential, it’s also entirely possible that it’s a unique insight. Please do attempt to publish it.
For an ‘off the top of my head’ example of this sort of modeling in the wild, this is a really interesting paper:
Basically, the model was “we’ve got a class of cancer cells with mitochondrial weirdness, what happens if we shut off both mitochondrial ribosomes at the same time?” And it turned out there were commonly available low dose drugs which do this.
This is actually done, quite a lot in fact, it’s just really hard and the search space is huge. Kudos to you for your analysis; it’s unlikely to be a major step forward, but given that idea search space is effectively exponential, it’s also entirely possible that it’s a unique insight. Please do attempt to publish it.
For an ‘off the top of my head’ example of this sort of modeling in the wild, this is a really interesting paper:
https://europepmc.org/article/pmc/pmc6520007
Basically, the model was “we’ve got a class of cancer cells with mitochondrial weirdness, what happens if we shut off both mitochondrial ribosomes at the same time?” And it turned out there were commonly available low dose drugs which do this.