Mega-scale asteroid impacts (dinosaur-killer size) come close. Uncertainty there would be about whether we could survive climatic disruptions better than the dinosaurs did (noting that fish, crocodiles, mammals, birds, etc, survived) using technology.
This doesn’t really answer the “man-made” part of “man-made extinction event” (unless you know something about mad scientists with ion engines mounted on large asteroids that I don’t know).
Sorry, I misread your question. I don’t think we have rigid uncontroversial frequentist estimates for any man-made extinction event. There are estimates I would say are unreasonably low, but there will be a step along the lines of “really?!? You seriously assign less than a 1 in 1 billion probability to there being a way for bioweapons programs of the next 50 years to create a set of overlapping long-latency high virulence pathogens that would get all of humanity, in light of mousepox and H5N1 experiments, the capabilities of synthetic biology, the results of these expert elicitations, etc?”
Mega-scale asteroid impacts (dinosaur-killer size) come close. Uncertainty there would be about whether we could survive climatic disruptions better than the dinosaurs did (noting that fish, crocodiles, mammals, birds, etc, survived) using technology.
This doesn’t really answer the “man-made” part of “man-made extinction event” (unless you know something about mad scientists with ion engines mounted on large asteroids that I don’t know).
Sorry, I misread your question. I don’t think we have rigid uncontroversial frequentist estimates for any man-made extinction event. There are estimates I would say are unreasonably low, but there will be a step along the lines of “really?!? You seriously assign less than a 1 in 1 billion probability to there being a way for bioweapons programs of the next 50 years to create a set of overlapping long-latency high virulence pathogens that would get all of humanity, in light of mousepox and H5N1 experiments, the capabilities of synthetic biology, the results of these expert elicitations, etc?”