Thanks! I’ve been conflicted about which SNP service to use, and now I don’t have to decide. :) Do you know if there are any potential downsides to consenting to let Veritas use the data for research? Would you tick that box?
I am not sure you necessarily want to use Veritas/Dante Labs (Veritas might be sold out already based on their Twitter), as WGS reports are usually pretty raw and you won’t get all of the interpretive services somebody like 23andMe would provide. I don’t believe 23andMe or the other major services let you just upload sequencing data either, only download. Offhand, I’m not sure how easy it would be to even use Promethease (not that Promethease is very worthwhile, as most of their report is candidate-gene junk). Personally, I am holding off on getting a WGSes done. I don’t know what I would do with mine, and the price should keep getting lower.
Oh, I misunderstood the purpose of your comment and thought you were recommending people to take advantage of the sale. I knew it was going to sell out quickly so I made the order prior to posting my question. (I gave consent for research since it said that I could withdraw that consent at any time.)
It looks like Veritas offers VCF file download so it’s compatible with Promethease but the format it uses only gives 16,000 genotypes. Also apparently Veritas used to provide the full BAM raw data, but no longer does, which is disappointing, so I’ll probably cancel my order and take advantage of the Dante $199 sale instead which does offer BAM. Looks like sequencing.com lets you upload a BAM file and offers a bunch of apps to do different analyses on it.
No, I was mentioning the sales because they offer a measurement of what WGS costs end to end now—presumably Veritas/Dante or Nebula are offering at close to their marginal cost (as they aren’t big or wealthy enough to afford to give it away and WGSes aren’t exactly a repeat-customer business). As far as Dante goes, I have seen some complaints about very slow or inconsistent service; on IRC, one of us did a previous sale and their original spit didn’t work, so they sent him another tube and forgot the postage. Not sure if he’s gotten his WGS yet either.
I see. Given that I haven’t done a genotype yet, would you suggest that I go through with Dante anyway, or wait until the price comes down further? (Presumably it would definitely be worth doing at $100?)
Well, do you have anything in mind specifically to do with it? If you do, it may not be worthwhile to wait. But if you don’t have something which needs to be done with a WGS right now, you probably aren’t going to be struck with inspiration once you get your download either.
Thanks! I’ve been conflicted about which SNP service to use, and now I don’t have to decide. :) Do you know if there are any potential downsides to consenting to let Veritas use the data for research? Would you tick that box?
Yes. In fact, I am already a PGP participant.
I am not sure you necessarily want to use Veritas/Dante Labs (Veritas might be sold out already based on their Twitter), as WGS reports are usually pretty raw and you won’t get all of the interpretive services somebody like 23andMe would provide. I don’t believe 23andMe or the other major services let you just upload sequencing data either, only download. Offhand, I’m not sure how easy it would be to even use Promethease (not that Promethease is very worthwhile, as most of their report is candidate-gene junk). Personally, I am holding off on getting a WGSes done. I don’t know what I would do with mine, and the price should keep getting lower.
Oh, I misunderstood the purpose of your comment and thought you were recommending people to take advantage of the sale. I knew it was going to sell out quickly so I made the order prior to posting my question. (I gave consent for research since it said that I could withdraw that consent at any time.)
It looks like Veritas offers VCF file download so it’s compatible with Promethease but the format it uses only gives 16,000 genotypes. Also apparently Veritas used to provide the full BAM raw data, but no longer does, which is disappointing, so I’ll probably cancel my order and take advantage of the Dante $199 sale instead which does offer BAM. Looks like sequencing.com lets you upload a BAM file and offers a bunch of apps to do different analyses on it.
No, I was mentioning the sales because they offer a measurement of what WGS costs end to end now—presumably Veritas/Dante or Nebula are offering at close to their marginal cost (as they aren’t big or wealthy enough to afford to give it away and WGSes aren’t exactly a repeat-customer business). As far as Dante goes, I have seen some complaints about very slow or inconsistent service; on IRC, one of us did a previous sale and their original spit didn’t work, so they sent him another tube and forgot the postage. Not sure if he’s gotten his WGS yet either.
I see. Given that I haven’t done a genotype yet, would you suggest that I go through with Dante anyway, or wait until the price comes down further? (Presumably it would definitely be worth doing at $100?)
Well, do you have anything in mind specifically to do with it? If you do, it may not be worthwhile to wait. But if you don’t have something which needs to be done with a WGS right now, you probably aren’t going to be struck with inspiration once you get your download either.