Uh this is kinda embarrassing but I just didn’t really read it at all honestly..
Q: when was prion disease discovered
A: “Prion disease was first recognized as a distinct category of neurodegenerative disorders in the 1980s, though the groundwork for its discovery was laid earlier.
Key milestones in the discovery of prion diseases include:
1920s: Creutzfeldt-Jakob Disease (CJD) was first described by Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
1950s: Carleton Gajdusek began studying kuru, a disease affecting the Fore people of Papua New Guinea.
1960s: Gajdusek demonstrated that kuru could be transmitted to chimpanzees, suggesting an infectious etiology.
1982: Stanley Prusiner coined the term “prion” (for proteinaceous infectious particle) and proposed the protein-only hypothesis for these infectious agents.
1997: Prusiner was awarded the Nobel Prize in Physiology or Medicine for his work on prions.
The concept of prions as the causative agents of these diseases was revolutionary because it challenged the central dogma of biology, suggesting that proteins alone, without nucleic acids, could be infectious.
Would you like me to elaborate on any specific aspect of prion disease discovery?”
What did Claude say, exactly?
Uh this is kinda embarrassing but I just didn’t really read it at all honestly..
Q: when was prion disease discovered
A: “Prion disease was first recognized as a distinct category of neurodegenerative disorders in the 1980s, though the groundwork for its discovery was laid earlier.
Key milestones in the discovery of prion diseases include:
1920s: Creutzfeldt-Jakob Disease (CJD) was first described by Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
1950s: Carleton Gajdusek began studying kuru, a disease affecting the Fore people of Papua New Guinea.
1960s: Gajdusek demonstrated that kuru could be transmitted to chimpanzees, suggesting an infectious etiology.
1982: Stanley Prusiner coined the term “prion” (for proteinaceous infectious particle) and proposed the protein-only hypothesis for these infectious agents.
1997: Prusiner was awarded the Nobel Prize in Physiology or Medicine for his work on prions.
The concept of prions as the causative agents of these diseases was revolutionary because it challenged the central dogma of biology, suggesting that proteins alone, without nucleic acids, could be infectious.
Would you like me to elaborate on any specific aspect of prion disease discovery?”