I actually missed those two negative studies—I only went through the first few pages of Google Scholar and PubMed results; I guess I should’ve been looking more closely at the preexisting discussion here. My confidence is lowered. Now for those two studies themselves -
The European one has a line in the abstract that seems to explain it: “No adenoviral DNA could be found using PCR on visceral adipose tissue.” That suggests either a significantly different strain or a significantly different (and better) immune response. I haven’t read the text of the military study (that one costs money), but the most likely confounding factor there would be military recruitment filtering out a lot of obese people; the child exposure test weakly suggests that the effect is largest on children whose adipose tissues are still growing, while the obese in the military are probably mostly those who started out fit and gained weight as they aged.
I actually missed those two negative studies—I only went through the first few pages of Google Scholar and PubMed results; I guess I should’ve been looking more closely at the preexisting discussion here. My confidence is lowered. Now for those two studies themselves -
The European one has a line in the abstract that seems to explain it: “No adenoviral DNA could be found using PCR on visceral adipose tissue.” That suggests either a significantly different strain or a significantly different (and better) immune response. I haven’t read the text of the military study (that one costs money), but the most likely confounding factor there would be military recruitment filtering out a lot of obese people; the child exposure test weakly suggests that the effect is largest on children whose adipose tissues are still growing, while the obese in the military are probably mostly those who started out fit and gained weight as they aged.
I have the text of the military study if you want to PM an email address.