I’m not sure how usefully these sorts of quantities would correlate. For example, there’s a couple of cases I read about where single individuals (probably immunocompromised) have produced thousands of times more sequencing abundance in wastewater than others. It might work out if you discard outliers like these?
I’m not sure how usefully these sorts of quantities would correlate. For example, there’s a couple of cases I read about where single individuals (probably immunocompromised) have produced thousands of times more sequencing abundance in wastewater than others. It might work out if you discard outliers like these?
People definitely vary in how much they shed, though thousands of times more than average sounds higher than I’ve seen?
At least with covid during the time when cases were tracked reasonably well there was a pretty close connection between covid levels in municipal wastewater and case rates. For example, see Nationwide Trends in COVID-19 Cases and SARS-CoV-2 RNA Wastewater Concentrations in the United States:
(Blue is wastewater concentration, orange is cases)