I would like to call attention to the conflict of interest statement at the end, where the senior author Charles Brenner is identified as chief scientific adviser of ChromaDex, maker of Tru Niagen, a profitable nicotinamide riboside supplement. I’m not saying the theory is necessarily wrong—NAD+ is implicated in many aspects of aging, and aging is obviously a risk factor for Covid mortality. But the effects of NR supplementation in humans have been a bit over-hyped in the past. Again, I don’t mean to imply that it does nothing, but it has been pushed as an anti-aging supplement without good evidence for improvement of biomarkers other than NAD+. For instance this study found no effect on insulin sensitivity or other metabolic measures.
As far as lung health goes, tuberculosis prevalence is inversely correlated with B3 (of any kind, not just NR). This isn’t some $@#! malaria drug or Ebola has-been, there’s no side-effect downside.
Is anyone using the short school day /two classes method? Given how the Finnish system works, it sounds promising.
Re susceptibility to SARS-CoV-2, I think this paper has a lot of the answer, especially for older people:
https://www.biorxiv.org/content/10.1101/2020.04.17.047480v2
I would like to call attention to the conflict of interest statement at the end, where the senior author Charles Brenner is identified as chief scientific adviser of ChromaDex, maker of Tru Niagen, a profitable nicotinamide riboside supplement. I’m not saying the theory is necessarily wrong—NAD+ is implicated in many aspects of aging, and aging is obviously a risk factor for Covid mortality. But the effects of NR supplementation in humans have been a bit over-hyped in the past. Again, I don’t mean to imply that it does nothing, but it has been pushed as an anti-aging supplement without good evidence for improvement of biomarkers other than NAD+. For instance this study found no effect on insulin sensitivity or other metabolic measures.
Sure, that’s why he disclosed. (Although you’re incorrect about “profitable”, so far ;)
But the Sinclair lab at Harvard hates Brenner, Iowa, and apple pie, yet came to similar conclusions:
https://www.preprints.org/manuscript/202004.0548/v1
As far as lung health goes, tuberculosis prevalence is inversely correlated with B3 (of any kind, not just NR). This isn’t some $@#! malaria drug or Ebola has-been, there’s no side-effect downside.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825668/
Thank you, lots of good info in those links.
Curve keeps dropping, hopefully this virus is as seasonal as most of its kind:
https://www.nbcnews.com/health/health-news/coronavirus-deaths-united-states-each-day-2020-n1177936